a-Isothiocyanatotoluene structure
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Common Name | a-Isothiocyanatotoluene | ||
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CAS Number | 622-78-6 | Molecular Weight | 149.213 | |
Density | 1.0±0.1 g/cm3 | Boiling Point | 243.8±9.0 °C at 760 mmHg | |
Molecular Formula | C8H7NS | Melting Point | 41 °C | |
MSDS | Chinese USA | Flash Point | 100.4±26.5 °C | |
Symbol |
GHS07, GHS08 |
Signal Word | Danger |
Use of a-IsothiocyanatotolueneBenzyl isothiocyanate is a member of natural isothiocyanates with antimicrobial activity[1][2]. Benzyl isothiocyanate potent inhibits cell mobility, migration and invasion nature and matrix metalloproteinase-2 (MMP-2) activity of murine melanoma cells[2]. |
Name | benzyl isothiocyanate |
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Synonym | More Synonyms |
Description | Benzyl isothiocyanate is a member of natural isothiocyanates with antimicrobial activity[1][2]. Benzyl isothiocyanate potent inhibits cell mobility, migration and invasion nature and matrix metalloproteinase-2 (MMP-2) activity of murine melanoma cells[2]. |
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Related Catalog | |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 243.8±9.0 °C at 760 mmHg |
Melting Point | 41 °C |
Molecular Formula | C8H7NS |
Molecular Weight | 149.213 |
Flash Point | 100.4±26.5 °C |
Exact Mass | 149.029922 |
PSA | 44.45000 |
LogP | 3.02 |
Vapour Pressure | 0.0±0.5 mmHg at 25°C |
Index of Refraction | 1.560 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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Symbol |
GHS07, GHS08 |
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Signal Word | Danger |
Hazard Statements | H302-H312-H315-H319-H332-H334-H335 |
Precautionary Statements | P261-P280-P305 + P351 + P338-P342 + P311 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | Xn: Harmful; |
Risk Phrases | R20/21/22 |
Safety Phrases | S26-S36/37/39 |
RIDADR | 2810 |
WGK Germany | 3 |
RTECS | NX8250000 |
Packaging Group | III |
Hazard Class | 8 |
Precursor 8 | |
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DownStream 10 | |
In vitro metabolic conversion of the organic breakdown products of glucosinolate to goitrogenic thiocyanate anion.
J. Sci. Food Agric. 95 , 2244-51, (2015) Glucosinolates are abundant in Brassicaceae vegetables, and they are degraded into various organic breakdown products (BPs) (R-CN, -NCS and -SCN) by myrosinase when plant tissues are damaged. This stu... |
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Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Curr. Drug Metab. 6 , 413-54, (2005) The inhibition of human cytochrome P450s (CYPs) is one of the most common mechanisms which can lead to drug-drug interactions. The inhibition of CYPs can be reversible (competitive or non-competitive)... |
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Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
J. Med. Chem. 53 , 5085-107, (2010)
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MFCD00004819 |
Toluene, α-isothiocyanato- |
(Isothiocyanatomethyl)benzene |
a-Isothiocyanatotoluene |
EINECS 210-753-9 |
Benzyl isothiocyanate |
Benzene, (isothiocyanatomethyl)- |