Teicoplanin

Modify Date: 2024-01-02 12:25:23

Teicoplanin Structure
Teicoplanin structure
Common Name Teicoplanin
CAS Number 61036-62-2 Molecular Weight 2526.73
Density 1.7±0.1 g/cm3 Boiling Point N/A
Molecular Formula C130H175Cl2N9O37R6 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Teicoplanin


Teicoplanin is a semisynthetic glycopeptide antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus faecalis.

 Names

Name Telicoplanin
Synonym More Synonyms

 Teicoplanin Biological Activity

Description Teicoplanin is a semisynthetic glycopeptide antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus faecalis.
Related Catalog

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Molecular Formula C130H175Cl2N9O37R6
Molecular Weight 2526.73
PSA 662.41000
LogP 0.40
Index of Refraction 1.754
Storage condition 2-8℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WY1559000
CHEMICAL NAME :
Teicoplanin
CAS REGISTRY NUMBER :
61036-62-2
LAST UPDATED :
198910

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
14 mg/kg/31D-I
TOXIC EFFECTS :
Sense Organs and Special Senses (Ear) - change in acuity
REFERENCE :
LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823- Volume(issue)/page/year: 1,613,1986

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
RTECS WY1559000

 Articles53

More Articles
Role of extra-cellular fatty acids in vancomycin induced biofilm formation by vancomycin resistant Staphylococcus aureus.

Pak. J. Pharm. Sci. 26(2) , 383-9, (2013)

In the present study a vancomycin resistant Staphylococcus aureus (S. aureus) (VRSA) (Labeled as CP2) was isolated from the blood of a post-operative cardiac patient is described. It harbors a plasmid...

A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.

Sci. Transl. Med. 7 , 290ra89, (2015)

Currently, no approved therapeutics exist to treat or prevent infections induced by Ebola viruses, and recent events have demonstrated an urgent need for rapid discovery of new treatments. Repurposing...

Once-weekly dalbavancin versus daily conventional therapy for skin infection.

N. Engl. J. Med. 370(23) , 2169-79, (2014)

Dalbavancin, a lipoglycopeptide antibiotic agent that is active against gram-positive pathogens, has a long plasma half-life, allowing for once-weekly dosing. DISCOVER 1 and DISCOVER 2 were identicall...

 Synonyms

teichomycin
TEICOPLANIN
(1S,2R,19R,22R,34S,37R,40R,52R)-2-[(2-Acetamido-2-deoxy-β-D-glucopyranosyl)oxy]-22-amino-5,15-dichloro-64-{[2-(decanoylamino)-2-deoxy-β-D-glucopyranosyl]oxy}-26,31,44,49-tetrahydroxy-47-(α-D -mannopyranosyloxy)-21,35,38,54,56,59-hexaoxo-7,13,28-trioxa-20,36,39,53,55,58-hexaazaundecacyclo[38.14.2.2.2.2.1.1.1.1.0.0]hexahexaconta-3,
 5,8(64),9,11,14,16,23(61),24,26,29(60),30,32
TEICOPLANIN,JP
Tagocid
TeicoplaninSodium
8327a
TEIC
Teicoplanin(sterile,non-sterile)
antibiotic8327a
Teocoplanin
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