3-Methoxybenzamide

Modify Date: 2024-01-02 13:39:49

3-Methoxybenzamide structure	Common Name	3-Methoxybenzamide
	CAS Number	5813-86-5	Molecular Weight	151.163
	Density	1.1±0.1 g/cm3	Boiling Point	280.0±23.0 °C at 760 mmHg
	Molecular Formula	C₈H₉NO₂	Melting Point	132.5-135.5 °C(lit.)
	MSDS	Chinese USA	Flash Point	146.8±18.9 °C

Use of 3-Methoxybenzamide

3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells[1]. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum)[2].

Name	3-methoxybenzamide
Synonym	More Synonyms

Description	3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells[1]. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum)[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
In Vitro	3-Methoxybenzamide (0-30 mM) affects septation via the FtsZ system during both vegetative growth and sporulation[1]. 3-Methoxybenzamide (3 MB; 0.2 to 0.6 mM) significantly increaseS the growth and microtuber formation of in vitro propagated plants[2]. Cell Viability Assay[1] Cell Line: ftsZ mutant strains. Concentration: 0-30 mM. Incubation Time: 30℃ overnight. Result: Changes directly or indirectly the ability of ftsZ to bind or hydrolyze the guanine nucleotide, ultimately leading to the inhibition of Zring formation.
References	[1]. Y Ohashi, et al. The lethal effect of a benzamide derivative, 3-methoxybenzamide, can be suppressed by mutations within a cell division gene, ftsZ, in Bacillus subtilis. J Bacteriol. 1999 Feb;181(4):1348-51. [2]. Venkateswari J. Chetty, et al. Poly (ADP-ribose) polymerase inhibitor 3-methoxybenzamide enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum). In Vitro Cellular & Developmental Biology - Plant (2020).

Density	1.1±0.1 g/cm3
Boiling Point	280.0±23.0 °C at 760 mmHg
Melting Point	132.5-135.5 °C(lit.)
Molecular Formula	C₈H₉NO₂
Molecular Weight	151.163
Flash Point	146.8±18.9 °C
Exact Mass	151.063324
PSA	52.32000
LogP	0.85
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.546

3-Methoxybenzamide MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV5463333

CHEMICAL NAME :: Benzamide, 3-methoxy-

CAS REGISTRY NUMBER :: 5813-86-5

BEILSTEIN REFERENCE NO. :: 2206857

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H9-N-O2

MOLECULAR WEIGHT :: 151.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 28,335,1994

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	CV5463333
HS Code	2924299090

Precursor 10
CAS#:591-31-1 m-Anisaldehyde CAS#:1711-05-3 3-Methoxybenzoy... CAS#:1527-89-5 3-Methoxybenzon... CAS#:5071-96-5 m-Anisylamine
CAS#:38489-80-4 3-methoxybenzal... CAS#:6971-51-3 3-Methoxybenzyl... CAS#:586-37-8 3'-Methoxyaceto... CAS#:586-38-9 3-Methoxybenzoi...
CAS#:57-13-6 Urea CAS#:100-84-5 3-Methylanisole
DownStream 10
CAS#:5071-96-5 m-Anisylamine CAS#:586-38-9 3-Methoxybenzoi... CAS#:2880-58-2 methoxybenzoquinone CAS#:18908-07-1 3-Methoxyphenyl...
CAS#:618-49-5 3-Hydroxybenzamide CAS#:6136-67-0 3-Ethoxybenzophenone CAS#:64559-06-4 3-Methoxybenzen... CAS#:132089-44-2 ETHYL 2-(3-METH...
CAS#:1527-89-5 3-Methoxybenzon... CAS#:16460-28-9 1,3-bis(3-metho...

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Characterization of the superinduction of the c-myc proto-oncogene in fibroblasts by benzamide derivatives.

Mol. Cell Biochem. 124(2) , 175-81, (1993)

In mouse fibroblasts stimulated from quiescence into proliferation by serum the induction of expression of the c-myc proto-oncogene is strongly stimulated by 3-methoxybenzamide. Similar superinduction...

Immunosuppressive activities of 6(5H)-phenanthridinone, a new poly(ADP-ribose)polymerase inhibitor.

Int. J. Immunopharmacol. 17(4) , 265-71, (1995)

6(5H)-phenanthridinone, a recently identified poly(ADP-ribose)polymerase (PARP) inhibitor, is able, at micromolar concentrations, to inhibit concanavalin A-induced lymphocyte proliferation and to pote...

Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ.

Bioorg. Med. Chem. Lett. 19 , 524-7, (2009)

3-Methoxybenzamide is a weak inhibitor of the essential bacterial cell division protein FtsZ. Exploration of the structure-activity relationships of 3-methoxybenzamide analogues led to the identificat...

3-Methoxybenzamide

MFCD00007986

3-Methoxy-benzoesaeure-amid

3-Methoxy-benzamid

3-methoxy-benzoic acid amide

m-anisamide

Benzamide, 3-methoxy-

Benzamide,3-methoxy

3-Methoxy-benzamide

EINECS 227-379-7

3-Methoxyphenylformamide

m-Methoxybenzamide

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 3-Methoxybenzamide
Price: ￥1129.0/25g ￥3609.0/100g ￥309.0/5g
Purity: 97.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: 3-Methoxybenzamide
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Benzamide, 3-methoxy-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 3-Methoxybenzamide
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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