Icariside I

Modify Date: 2024-01-02 18:13:37

Icariside I structure	Common Name	Icariside I
	CAS Number	56725-99-6	Molecular Weight	530.521
	Density	1.5±0.1 g/cm3	Boiling Point	801.3±65.0 °C at 760 mmHg
	Molecular Formula	C₂₇H₃₀O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	267.8±27.8 °C

Use of Icariside I

Icariside I is a metabolite of Icarlin, which could regulate bone remodeling and is recognized as an effective agent for the treatment of osteoporosis.

Name	3,5-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
Synonym	More Synonyms

Description	Icariside I is a metabolite of Icarlin, which could regulate bone remodeling and is recognized as an effective agent for the treatment of osteoporosis.
Related Catalog	Signaling Pathways >> Others >> Others Natural Products >> Flavonoids Research Areas >> Others
References	[1]. Cheng T, et al. Metabolism profiles of icariin in rats using ultra-high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry and in vitro enzymatic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 15;1033-1034:353-360. [2]. Ming LG, et al. Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling. J Cell Physiol. 2013 Mar;228(3):513-21.

Description

Icariside I is a metabolite of Icarlin, which could regulate bone remodeling and is recognized as an effective agent for the treatment of osteoporosis.

Related Catalog

Signaling Pathways >> Others >> Others

Natural Products >> Flavonoids

Research Areas >> Others

References

[1]. Cheng T, et al. Metabolism profiles of icariin in rats using ultra-high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry and in vitro enzymatic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 15;1033-1034:353-360.

[2]. Ming LG, et al. Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling. J Cell Physiol. 2013 Mar;228(3):513-21.

Density	1.5±0.1 g/cm3
Boiling Point	801.3±65.0 °C at 760 mmHg
Molecular Formula	C₂₇H₃₀O₁₁
Molecular Weight	530.521
Flash Point	267.8±27.8 °C
Exact Mass	530.178833
PSA	179.28000
LogP	2.60
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.664
Storage condition	2-8C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ2984200

CHEMICAL NAME :: 4H-1-Benzopyran-4-one, 3,5-dihydroxy-7-(beta-D-glucopyranosyloxy)-2-(4-metho xyphenyl)-8- (3-methyl-2-butenyl)-

CAS REGISTRY NUMBER :: 56725-99-6

BEILSTEIN REFERENCE NO. :: 0072036

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C27-H30-O11

MOLECULAR WEIGHT :: 530.57

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Mammal - species unspecified Leukocyte

DOSE/DURATION :: 625 ug/L

REFERENCE :: CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 53,175,1990

Lcariside I

icariside II

Baohuoside-1

icarisid I

3,5-Dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4-oxo-4H-chromen-7-yl β-D-glucopyranoside

4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-3,5-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-

Icariside I

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Icariside I
Price: ￥988.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Icariside I
Price: $550.0/100mg $1100.0/250mg $2200.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: LCARISIDE I
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Icariside I

Use of Icariside I

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Icariside I Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Synonyms