Rosmarinic acid

Modify Date: 2024-01-02 14:06:44

Rosmarinic acid Structure
Rosmarinic acid structure
Common Name Rosmarinic acid
CAS Number 537-15-5 Molecular Weight 360.315
Density 1.5±0.1 g/cm3 Boiling Point 694.7±55.0 °C at 760 mmHg
Molecular Formula C18H16O8 Melting Point 171-175ºC(lit.)
MSDS N/A Flash Point 254.5±25.0 °C

 Use of Rosmarinic acid


Rosmarinic acid racemate is the racemate of Rosmarinic acid. Rosmarinic acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.

 Names

Name rosmarinic acid
Synonym More Synonyms

 Rosmarinic acid Biological Activity

Description Rosmarinic acid racemate is the racemate of Rosmarinic acid. Rosmarinic acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Andrade JM, et al. Combining in vitro and in silico approaches to evaluate the multifunctional profile of rosmarinic acid from Blechnum brasiliense on targets related to neurodegeneration. Chem Biol Interact. 2016 Jul 25;254:135-45.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 694.7±55.0 °C at 760 mmHg
Melting Point 171-175ºC(lit.)
Molecular Formula C18H16O8
Molecular Weight 360.315
Flash Point 254.5±25.0 °C
Exact Mass 360.084503
PSA 144.52000
LogP 1.70
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.714

 Safety Information

Hazard Codes Xi
Risk Phrases R36/38
Safety Phrases 26-37/39
HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

benzenepropanoic acid, α-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-
Rosmarinate
3-(3,4-Dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}propanoic acid
3-METHYL-2-BUTENYLTHIOPHENE
Rosemary acid
Rosmarinic acid
Rose thiophene
3-(3,4-Dihydroxy-phenyl)-acrylic acid 1-carboxy-2-(3,4-dihydroxy-phenyl)-ethyl ester
Rosmarin-saeure
3-(3,4-Dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid
Benzenepropanoic acid, α-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-
Rosmarinic acid (racemate)
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