Esflurbiprofen
Modify Date: 2024-01-02 19:53:52
Esflurbiprofen structure
|
Common Name | Esflurbiprofen | ||
|---|---|---|---|---|
| CAS Number | 51543-39-6 | Molecular Weight | 244.261 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 376.2±30.0 °C at 760 mmHg | |
| Molecular Formula | C15H13FO2 | Melting Point | 109-110ºC(lit.) | |
| MSDS | N/A | Flash Point | 181.3±24.6 °C | |
Use of Esflurbiprofen(S)-Flurbiprofen is an active enantiomer of Flurbiprofen, with IC50 values of 0.48 μM and 0.47 μM for COX-1 and COX-2, respectively[1]. |
| Name | (S)-flurbiprofen |
|---|---|
| Synonym | More Synonyms |
| Description | (S)-Flurbiprofen is an active enantiomer of Flurbiprofen, with IC50 values of 0.48 μM and 0.47 μM for COX-1 and COX-2, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
COX-1:0.48 μM (IC50) COX-2:0.47 μM (IC50) |
| In Vitro | (S)-Flurbiprofen (10–7 M) results in a total suppression of basal and stimulated PGE2 release in rat skin[2]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 376.2±30.0 °C at 760 mmHg |
| Melting Point | 109-110ºC(lit.) |
| Molecular Formula | C15H13FO2 |
| Molecular Weight | 244.261 |
| Flash Point | 181.3±24.6 °C |
| Exact Mass | 244.089951 |
| PSA | 37.30000 |
| LogP | 4.11 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.568 |
| Hazard Codes | T |
|---|---|
| Risk Phrases | R25 |
| Safety Phrases | 36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| [1,1'-biphenyl]-4-acetic acid, 2-fluoro-a-methyl- |
| 2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetic acid |
| 2-FLUORO-α-METHYL-4-BIPHENYLACETIC ACID |
| 2-(2-Fluoro-4-biphenylyl)propanoic acid |
| Froben |
| Anside |
| EINECS 257-263-1 |
| d-Flurbiprofen |
| [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl- |
| Stayban |
| Esflurbiprofen |
| MFCD00866152 |
| (S)-Flurbiprofen |
| 2-(2-fluorobiphenyl-4-yl)propanoic acid |
| Ocufen |
| Ansaid |
| (±)-Flurbiprofen |
| 2-(2-fluoro-4-biphenylyl)propionic acid |
| Zepolas |
| Adfeed |
| rac-Flurbiprofen |
| tarenflurbil |
| Flurbiprofen |