Glufosinate

Modify Date: 2024-01-04 13:09:01

Glufosinate Structure
Glufosinate structure
Common Name Glufosinate
CAS Number 51276-47-2 Molecular Weight 181.12700
Density 1.378 g/cm3 Boiling Point 519.1ºC at 760 mmHg
Molecular Formula C5H12NO4P Melting Point 230ºC
MSDS N/A Flash Point 267.7ºC

 Use of Glufosinate


Glufosinate, a phosphinic acid analogue of glutamic acid, is a herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate exerts neurotoxic activity[1][2].

 Names

Name phosphinothricin
Synonym More Synonyms

 Glufosinate Biological Activity

Description Glufosinate, a phosphinic acid analogue of glutamic acid, is a herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate exerts neurotoxic activity[1][2].
Related Catalog
In Vitro Glufosinate (1-100 μM; 12DIV) disrupts cell-cell adhesion in differentiated V-SVZ neural stem cells (NSCs)[2]. Glufosinate (1-100 μM; 12DIV) significantly decreases Celsr2 gene expression at 100 μM[2]. Glufosinate impairs ependymal cell capability to synthetize cilia[2].
In Vivo Glufosinate (10-250 mg/kg; gavage; Daily; on days 6-15 of gestation) indicates maternal toxicity in the groups given 50 or 250 mg/kg in Wistar rats[3]. The Elimination of Glufosinate (oral intubation) in the blood takes place with a half-life of less than 4 hours in male and female rats[3].
References

[1]. Áy Z, et al. The effect of high concentrations of glufosinate ammonium on the yield components of transgenic spring wheat (Triticum aestivum L.) constitutively expressing the bar gene. ScientificWorldJournal. 2012;2012:657945.

[2]. Feat-Vetel J, et al. Multiple effects of the herbicide glufosinate-ammonium and its main metabolite on neural stem cells from the subventricular zone of newborn mice. Neurotoxicology. 2018 Dec;69:152-163.

[3]. Ebert E, et al. Summary of safety evaluation toxicity studies of glufosinate ammonium. Food Chem Toxicol. 1990 May;28(5):339-49.

 Chemical & Physical Properties

Density 1.378 g/cm3
Boiling Point 519.1ºC at 760 mmHg
Melting Point 230ºC
Molecular Formula C5H12NO4P
Molecular Weight 181.12700
Flash Point 267.7ºC
Exact Mass 181.05000
PSA 110.43000
LogP 0.38890
Index of Refraction 1.5

 Safety Information

Hazard Codes Xn
HS Code 2931900090

 Precursor & DownStream

Precursor  0

DownStream  1

 Customs

HS Code 2931900090
Summary 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

 Synonyms

2-amino-4-(hydroxymethylphosphinyl)butyric acid
(2RS)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyric acid
4-[hydroxy(methyl)phosphinoyl]-DL-homoalanine
2-amino-4-(hydroxymethylphosphinyl)butanoic acid
glufosinate