1,3-Dithiane

Modify Date: 2024-01-02 19:14:31

1,3-Dithiane structure	Common Name	1,3-Dithiane
	CAS Number	505-23-7	Molecular Weight	120.236
	Density	1.1±0.1 g/cm3	Boiling Point	195.0±23.0 °C at 760 mmHg
	Molecular Formula	C₄H₈S₂	Melting Point	52-54 °C(lit.)
	MSDS	Chinese USA	Flash Point	90.6±0.0 °C

Use of 1,3-Dithiane

1,3-Dithiane is a protected formaldehyde anion equivalent that could serve as a useful labeled synthon[1]. 1,3-Dithiane is also a sulfur-containing Maillard reaction products (MRPs) found in boiled beef extracts. 1,3-Dithiane shows a potent direct-acting mutagenicity toward S. typhimurium TA98 and TA100[2].

Name	1,3-dithiane
Synonym	More Synonyms

Description	1,3-Dithiane is a protected formaldehyde anion equivalent that could serve as a useful labeled synthon[1]. 1,3-Dithiane is also a sulfur-containing Maillard reaction products (MRPs) found in boiled beef extracts. 1,3-Dithiane shows a potent direct-acting mutagenicity toward S. typhimurium TA98 and TA100[2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	Human Endogenous Metabolite
References	[1]. Lee H, et al. Genotoxicity of 1,3-dithiane and 1,4-dithiane in the CHO/SCE assay and the Salmonella/microsomal test. Mutat Res. 1994 Jun;321(4):213-8. [2]. Martinez RA, et al. Synthesis of isotopically labeled 1,3-dithiane. J Labelled Comp Radiopharm. 2014 May 15;57(5):338-41.

Density	1.1±0.1 g/cm3
Boiling Point	195.0±23.0 °C at 760 mmHg
Melting Point	52-54 °C(lit.)
Molecular Formula	C₄H₈S₂
Molecular Weight	120.236
Flash Point	90.6±0.0 °C
Exact Mass	120.006737
PSA	50.60000
LogP	1.14
Vapour Pressure	0.6±0.4 mmHg at 25°C
Index of Refraction	1.574

1,3-Dithiane MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JO5070000

CHEMICAL NAME :: m-Dithiane

CAS REGISTRY NUMBER :: 505-23-7

LAST UPDATED :: 199412

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H8-S2

MOLECULAR WEIGHT :: 120.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 80 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 321,213,1994

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	20/21/22
Safety Phrases	S22-S24/25
RIDADR	UN 1325 4.1/PG 2
WGK Germany	3
RTECS	JO5070000
Packaging Group	III
Hazard Class	4.1
HS Code	29349990

Precursor 10
CAS#:109-80-8 1,3-Propanedithiol CAS#:109-87-5 dimethoxymethane CAS#:75-11-6 Diiodomethane CAS#:69178-10-5 1,3-Dithiane,2-...
CAS#:462-95-3 diethoxymethane CAS#:50-00-0 Formaldehyde CAS#:120-57-0 piperonal CAS#:13411-42-2 1,3-dithian-2-y...
CAS#:75-15-0 Carbon disulphide CAS#:109-64-8 1,3-Dibromopropane
DownStream 10
CAS#:111897-16-6 2-tetradecyl-1,... CAS#:111741-88-9 2-[4-(1,3-dithi... CAS#:104863-72-1 Ethanone, 1-(1,... CAS#:5425-44-5 1,3-Dithiane, 2...
CAS#:53885-35-1 Ticlopidine Hyd... CAS#:14947-48-9 2-(1,3-dithian-... CAS#:14758-37-3 2-methylsulfany... CAS#:39141-54-3 2,2-bis(methylt...
CAS#:21777-32-2 hexanal-1,3-dithiane CAS#:26413-18-3 1,3-dithiane 1,...

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Genotoxicity of 1,3-dithiane and 1,4-dithiane in the CHO/SCE assay and the Salmonella/microsomal test.

Mutat. Res. 321(4) , 213-8, (1994)

1,3-Dithiane and 1,4-dithiane are the sulfur-containing Maillard reaction products (MRPs) which have been found in boiled beef extracts. In this study the genotoxicity of these products was examined u...

Synthesis and applications of masked oxo-sulfinamides in asymmetric synthesis.

Org. Biomol. Chem. 10(26) , 5021-31, (2012)

This short perspective reports on the synthesis and applications of a class of chiral amino carbonyl compounds, masked oxo-sulfinamides where the amine is protected with an N-sulfinyl moiety and the c...

Au(PPh(3))Cl-AgSbF(6)-catalyzed rearrangement of propargylic 1,3-dithianes: formation of 8-membered 1,3-bisthio-substituted cyclic allenes.

Chem. Commun. (Camb.) (18) , 2535-7, (2009)

Au(PPh(3))Cl-AgSbF(6)-catalyzed rearrangement of propargylic 1,3-dithiane leads to the formation of 8-membered dithio-substituted cyclic allenes, which are remarkably stable.

Dithiane-1,3

1,3-Dithiacyclohexane

1,3-dithaine

EINECS 208-006-7

META-DITHIANE

[1,3]dithiane

1,3-Dithian

1,3-dihtiane

M-DITHIANE

1,3-Dithiane

1,3-Dithane

MFCD00006654

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1,3-Dithiane
Price: ￥928.0/25g ￥228.0/5g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,3-Dithiane
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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