Thymidine

Modify Date: 2024-01-02 18:43:17

Thymidine structure	Common Name	Thymidine
	CAS Number	50-89-5	Molecular Weight	242.229
	Density	1.6±0.1 g/cm3	Boiling Point	510.1±60.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₄N₂O₅	Melting Point	187-189ºC
	MSDS	Chinese USA	Flash Point	262.3±32.9 °C

Use of Thymidine

Thymidine is a a pyrimidine deoxynucleoside.

Name	thymidine
Synonym	More Synonyms

Description	Thymidine is a a pyrimidine deoxynucleoside.
Related Catalog	Natural Products >> Alkaloid Research Areas >> Others
Target	Human Endogenous Metabolite
References	[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.

Density	1.6±0.1 g/cm3
Boiling Point	510.1±60.0 °C at 760 mmHg
Melting Point	187-189ºC
Molecular Formula	C₁₀H₁₄N₂O₅
Molecular Weight	242.229
Flash Point	262.3±32.9 °C
Exact Mass	242.090271
PSA	104.55000
LogP	-0.90
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.674

Thymidine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XP2071000

CHEMICAL NAME :: Thymidine

CAS REGISTRY NUMBER :: 50-89-5

LAST UPDATED :: 199710

DATA ITEMS CITED :: 28

MOLECULAR FORMULA :: C10-H14-N2-O5

MOLECULAR WEIGHT :: 242.26

WISWESSER LINE NOTATION :: T6NVMVJ E1 A- ET5OTJ B1Q CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2512 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 400 mg/kg

SEX/DURATION :: female 11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 20 gm/kg

SEX/DURATION :: male 5 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 800 mg/kg

SEX/DURATION :: female 8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Unscheduled DNA synthesis

TYPE OF TEST :: DNA inhibition

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Sperm Morphology

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 150 mmol/L

REFERENCE :: PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 48,686,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7245 No. of Facilities: 213 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 578 (estimated) No. of Female Employees: 141 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R20/21/22
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XP2071000

Precursor 9
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DownStream 10
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1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione

1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-5-methyl-2(1H)-pyrimidinone

Thymidine

1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one

2'-deoxy-5-methyluridine

2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-.β.-D-erythro-pentofuranosyl)-5-methyl-

T6NVMVJ E1 A- ET5OTJ B1Q CQ &&Ribo Form

2,4(1H,3H)-Pyrimidinedione,1-(2-deoxy-.Beta.-D-erythro-pentofuranosyl)-5-methyl

SS-THYMIDINE

2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-methyl-

Thyminedeoxyriboside

2'-dT

1-(2-Deoxy-b-D-ribofuranosyl)-5-methyluracil

Zidovudine Related Compound D

EINECS 200-070-4

deoxyribosylthymine

deoxythymidine

DTHD

1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil

Thymine-2-deoxyriboside

1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methylpyrimidin-2,4(1H,3H)-dion

2'-Deoxythymidine

Thymine deoxyriboside

2(1H)-pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-5-methyl-

3,4-Dihydrothymidine, 2'-deoxy-

2'-deoxy-5-methyl-Uridine

5-Methyldeoxyuridine

3H-Thymidine

1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione

Dthyd

1-(2-Deoxy-β-D-ribofuranosyl)thymine

MFCD00006537

5-methyl-2'-deoxyuridine

b-Thymidine

Thymidin

BioBioPha
China
Product Name: Thymidine
Price: ￥Inquiry/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Thymidine
Price: ￥478.0/5mg ￥228.0/25g ￥658.0/100g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Thymidine
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Thymidine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Thymidine
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: thymidine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Price: ￥550/10 mM * 1 mL in DMSO

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Thymidine

Use of Thymidine

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Thymidine Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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