Tigloidin structure
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Common Name | Tigloidin | ||
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CAS Number | 495-83-0 | Molecular Weight | 223.31100 | |
Density | 1.06g/cm3 | Boiling Point | 290.2ºC at 760 mmHg | |
Molecular Formula | C13H21NO2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 99.9ºC |
Use of TigloidinTigloidin is an analogue of atropine, with anticholinergic activity. |
Name | (3-exo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (2E)-2-methyl-2-bute noate |
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Synonym | More Synonyms |
Description | Tigloidin is an analogue of atropine, with anticholinergic activity. |
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Related Catalog | |
In Vivo | Tigloidine hydrobromide (20-60 mg/kg, i.p.) fails to protect the mice against the lethal effect of physostigmine, but at 100 mg/kg and above, it protects 80% of the animals against the lethal effect. Tigloidine markedly prevents tremor and salivation produced by tremorine at 80-100 mg/kg, but fails to prevent these effects in doses up to 40 mg/kg. Tigloidine (up to 100 mg/kg, i.p) does not significantly affects reserpine and tetrabenazine induced sedation and ptosis in mice. Tigloidine (25-50 mg/kg, i.p.) also fails to cause any behavioral changes in the cats[1]. |
References |
Density | 1.06g/cm3 |
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Boiling Point | 290.2ºC at 760 mmHg |
Molecular Formula | C13H21NO2 |
Molecular Weight | 223.31100 |
Flash Point | 99.9ºC |
Exact Mass | 223.15700 |
PSA | 29.54000 |
LogP | 2.05890 |
Vapour Pressure | 0.0021mmHg at 25°C |
Index of Refraction | 1.514 |
Storage condition | 2-8℃ |
~% Tigloidin CAS#:495-83-0 |
Literature: Rabot; Peerless; Robins Phytochemistry, 1995 , vol. 39, # 2 p. 315 - 322 |
~% Tigloidin CAS#:495-83-0 |
Literature: Barger et al. Journal of the Chemical Society, 1937 , p. 1820,1823 |
(E)-2-methylbut-2-enoic acid methyl ester |
Methyl-2-methylcrotonat |
methyl 2-methylcrotonate |
2-Carbomethoxy-2-bute |
methylalpha-methylcrotonate |
tiglic acid methyl ester |
(E)-methyl 2-methylbut-2-enoate |
dimethylacrylic acid methyl ester |
Tiglinsaeure-tropan-3exo-ylester |
methyl (E)-2,3-dimethylpropenolate |
Tiglic acid methyl |
Methyltiglate |
tiglic acid tropane-3exo-yl ester |
2-methyl-but-2-enoic acid methyl ester |
methyl(e)-2-methylcrotonate |
Tigloidin |