Oxo Thiamine

Modify Date: 2024-01-04 15:48:26

Oxo Thiamine structure	Common Name	Oxo Thiamine
	CAS Number	490-82-4	Molecular Weight	280.34600
	Density	1.378g/cm3	Boiling Point	507ºC at 760mmHg
	Molecular Formula	C₁₂H₁₆N₄O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	260.4ºC

Name	3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one
Synonym	More Synonyms

Density	1.378g/cm3
Boiling Point	507ºC at 760mmHg
Molecular Formula	C₁₂H₁₆N₄O₂S
Molecular Weight	280.34600
Flash Point	260.4ºC
Exact Mass	280.09900
PSA	122.27000
LogP	1.06310
Vapour Pressure	4.23E-11mmHg at 25°C
Index of Refraction	1.662
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ7054240

CHEMICAL NAME :: (3H)-Thiazolone, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydro xyethyl)-4-methyl-

CAS REGISTRY NUMBER :: 490-82-4

BEILSTEIN REFERENCE NO. :: 0310984

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H16-N4-O2-S

MOLECULAR WEIGHT :: 280.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 530 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 23,69,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 730 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 23,69,1968

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 23,69,1968

Precursor 8
CAS#:100502-51-0 thiamine disulfide CAS#:67-16-3 Thiamine Disulf... CAS#:1062-44-8 [3-(4-amino-2-m... CAS#:67-03-8 Thiamine hydroc...
CAS#:22580-38-7 3-(4-amino-2-me... CAS#:299-35-4 Thiothiamine CAS#:95-02-3 4-AMINO-5-AMINO... CAS#:13045-13-1 3-chloro-5-hydr...
DownStream 0

Thiamine thiazolone

3-(4-Amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-aethyl)-4-methyl-3H-thiazol-2-on

2(3h)-thiazolone,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl

3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-3H-thiazol-2-one

3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-(3H)-thiazolone

thiamine thiazolin-2-one

Thiaminthiazolone

Oxo Thiamine

Tiamintiazolone [Italian]

EINECS 207-719-0

(3H)-Thiazolone,3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl

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