5-Valine-angiotensin I

Modify Date: 2024-01-09 11:08:56

5-Valine-angiotensin I Structure
5-Valine-angiotensin I structure
Common Name 5-Valine-angiotensin I
CAS Number 484-43-5 Molecular Weight 1282.45000
Density 1.44g/cm3 Boiling Point N/A
Molecular Formula C61H87N17O14 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of 5-Valine-angiotensin I


5-Valine-angiotensin I is an Ang I peptide belonging to angiotensin I. 5-Valine-angiotensin I induces muscle contraction, can be used for renin-angiotensin system studies. Angiotensin I is a putative neurotransmitter, is the precursor of angiotensin II and of angiotensin fragment 1-7, which are involved in regulation of fluid volume and the release of aldosterone[1][2].

 Names

Name asp-arg-val-tyr-val-his-pro-phe-his-leu
Synonym More Synonyms

 5-Valine-angiotensin I Biological Activity

Description 5-Valine-angiotensin I is an Ang I peptide belonging to angiotensin I. 5-Valine-angiotensin I induces muscle contraction, can be used for renin-angiotensin system studies. Angiotensin I is a putative neurotransmitter, is the precursor of angiotensin II and of angiotensin fragment 1-7, which are involved in regulation of fluid volume and the release of aldosterone[1][2].
Related Catalog
In Vitro 5-Valine-angiotensin I shows myotropic effect (muscle contraction) on isolated rat colon after nonspecific desensitization of receptors with acetylcholine[2].

 Chemical & Physical Properties

Density 1.44g/cm3
Molecular Formula C61H87N17O14
Molecular Weight 1282.45000
Exact Mass 1281.66000
PSA 493.22000
LogP 3.44270
Index of Refraction 1.671
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles3

More Articles
Renal responses to AT1 receptor blockade.

Am. J. Hypertens. 13 , 45S-54S, (2000)

Because of the importance of the renin-angiotensin system in the pathophysiology of hypertension and in mediating associated alterations in renal function, angiotensin II (Ang II) AT1 receptor blocker...

Purification and identification of endogenous anti-opioid substances from bovine brain.

Biochem. Biophys. Res. Commun. 126(1) , 587-93, (1985)

Two fractions with high potency for reversing the inhibitory effect of Met-enkephalin on the electrically induced contractility of guinea-pig ileum have been purified from bovine brain extract. Unexpe...

Determination of renin activity in human plasma by column-switching high-performance liquid chromatography with fluorescence detection. Miyazaki T, Kai M, Ohkura Y.

J. Chromatogr. A. 490 , 43-51, (1989)

 Synonyms

[Val5]-Angiotensin I bovine
Asp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu-OH
L-Asp-L-Arg-L-Val-L-Tyr-L-Val-L-His-L-Pro-L-Phe-L-His-L-Leu-OH