4-(Dimethylamino)benzoyl chloride

Modify Date: 2024-01-06 15:23:04

4-(Dimethylamino)benzoyl chloride Structure
4-(Dimethylamino)benzoyl chloride structure
Common Name 4-(Dimethylamino)benzoyl chloride
CAS Number 4755-50-4 Molecular Weight 183.635
Density 1.2±0.1 g/cm3 Boiling Point 279.0±23.0 °C at 760 mmHg
Molecular Formula C9H10ClNO Melting Point 145-149 °C(lit.)
MSDS Chinese USA Flash Point 122.5±22.6 °C
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 4-dimethylaminobenzoyl chloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 279.0±23.0 °C at 760 mmHg
Melting Point 145-149 °C(lit.)
Molecular Formula C9H10ClNO
Molecular Weight 183.635
Flash Point 122.5±22.6 °C
Exact Mass 183.045090
PSA 20.31000
LogP 2.63
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.575

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C: Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 3261 8/PG 2
WGK Germany 3
Packaging Group III
Hazard Class 8
HS Code 2922499990

 Synthetic Route

~99%

4-(Dimethylamino)benzoyl chloride Structure

4-(Dimethylamin...

CAS#:4755-50-4

Literature: Keenan, Martine; Abbott, Michael J.; Alexander, Paul W.; Armstrong, Tanya; Best, Wayne M.; Berven, Bradley; Botero, Adriana; Chaplin, Jason H.; Charman, Susan A.; Chatelain, Eric; Von Geldern, Thomas W.; Kerfoot, Maria; Khong, Andrea; Nguyen, Tien; McManus, Joshua D.; Morizzi, Julia; Ryan, Eileen; Scandale, Ivan; Thompson, R. Andrew; Wang, Sen Z.; White, Karen L. Journal of Medicinal Chemistry, 2012 , vol. 55, # 9 p. 4189 - 4204

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4-(Dimethylamino)benzoyl chloride Structure

4-(Dimethylamin...

CAS#:4755-50-4

Literature: Meisenheimer; v. Budkewicz; Kananow Justus Liebigs Annalen der Chemie, 1921 , vol. 423, p. 90,91

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4-(Dimethylamino)benzoyl chloride Structure

4-(Dimethylamin...

CAS#:4755-50-4

Literature: Staudinger; Stockmann Chemische Berichte, 1909 , vol. 42, p. 3491

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4-(Dimethylamino)benzoyl chloride Structure

4-(Dimethylamin...

CAS#:4755-50-4

Literature: Kiprianow; Schrubowitsch Zhurnal Obshchei Khimii, 1956 , vol. 26, p. 2891,2895; engl. Ausg. S. 3215, 3219

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4-(Dimethylamino)benzoyl chloride Structure

4-(Dimethylamin...

CAS#:4755-50-4

Literature: Meisenheimer; v. Budkewicz; Kananow Justus Liebigs Annalen der Chemie, 1921 , vol. 423, p. 90,91

~%

4-(Dimethylamino)benzoyl chloride Structure

4-(Dimethylamin...

CAS#:4755-50-4

Literature: Meisenheimer; v. Budkewicz; Kananow Justus Liebigs Annalen der Chemie, 1921 , vol. 423, p. 90,91

~%

4-(Dimethylamino)benzoyl chloride Structure

4-(Dimethylamin...

CAS#:4755-50-4

Literature: Dadali, V. A.; Zubareva, T. M.; Litvinenko, L. M.; Simanenko, Yu. S. Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, # 8 p. 1543 - 1551 Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 8 p. 1695 - 1704

~%

4-(Dimethylamino)benzoyl chloride Structure

4-(Dimethylamin...

CAS#:4755-50-4

Literature: Rivier; Richards Helvetica Chimica Acta, 1925 , vol. 8, p. 494

~%

4-(Dimethylamino)benzoyl chloride Structure

4-(Dimethylamin...

CAS#:4755-50-4

Detail
Literature: Staudinger; Stockmann Chemische Berichte, 1909 , vol. 42, p. 3491

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Articles2

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Design and synthesis of labeling reagents (MS probes) for highly sensitive electrospray ionization mass spectrometry and their application to the detection of carbonyl, alcohol, carboxylic acid and primary amine samples.

Anal. Sci. 20 , 475-482, (2004)

Novel labeling reagents, called MS probes, which possess a positively charged quaternary amine moiety and can transform a neutral analyte into a charged compound by simply mixing with the analyte and ...

Oligosaccharide sensing with chromophore-modified curdlan in aqueous media.

Chem. Commun. (Camb.) 46(48) , 9128-30, (2010)

A newly synthesized chromophore-modified curdlan functions as a saccharide chemosensor in aqueous solution, enabling us to discriminate tetrasaccharide acarbose from 24 mono-, di-, tri-, and tetrasacc...

 Synonyms

MFCD00236039
4-(Dimethylamino)benzoyl chloride
4-Dimethylaminobenzoyl chloride
Benzoyl chloride, 4-(dimethylamino)-
4-(Dimethylamino)-benzoyl chloride