L-5-Hydroxytryptophan structure
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Common Name | L-5-Hydroxytryptophan | ||
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CAS Number | 4350-09-8 | Molecular Weight | 220.22 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | 520.6±50.0 °C at 760 mmHg | |
Molecular Formula | C11H12N2O3 | Melting Point | 270 °C (dec.)(lit.) | |
MSDS | Chinese USA | Flash Point | 268.7±30.1 °C | |
Symbol |
GHS06 |
Signal Word | Danger |
Use of L-5-HydroxytryptophanL-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist[1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia[2][3][4][5]. |
Name | 5-hydroxy-L-tryptophan |
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Synonym | More Synonyms |
Description | L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist[1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia[2][3][4][5]. |
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Related Catalog | |
Target |
Human Endogenous Metabolite |
References |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 520.6±50.0 °C at 760 mmHg |
Melting Point | 270 °C (dec.)(lit.) |
Molecular Formula | C11H12N2O3 |
Molecular Weight | 220.22 |
Flash Point | 268.7±30.1 °C |
Exact Mass | 220.084793 |
PSA | 99.34000 |
LogP | -0.14 |
Vapour Pressure | 0.0±1.4 mmHg at 25°C |
Index of Refraction | 1.737 |
Water Solubility | Slightly soluble |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Symbol |
GHS06 |
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Signal Word | Danger |
Hazard Statements | H301-H315-H319-H335 |
Precautionary Statements | Missing Phrase - N15.00950417-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
Hazard Codes | Xn:Harmful; |
Risk Phrases | R22 |
Safety Phrases | S36-S26 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | YN7110000 |
Packaging Group | III |
Hazard Class | 6.1 |
HS Code | 2929909090 |
~43% L-5-Hydroxytryp... CAS#:4350-09-8 |
Literature: Ube Industries, Ltd. Patent: US4497957 A1, 1985 ; |
~11%
Detail
|
Literature: Pharmazie, , vol. 40, # 11 p. 811 - 811 |
~% L-5-Hydroxytryp... CAS#:4350-09-8 |
Literature: Journal of Organic Chemistry, , vol. 22, p. 306,307 |
~68% L-5-Hydroxytryp... CAS#:4350-09-8 |
Literature: Berg, E. M. M. van den; Jansen, F. J. H. M.; Goede, A. T. J. W. de; Baldew, A. U.; Lugtenburg, J. Recueil des Travaux Chimiques des Pays-Bas, 1990 , vol. 109, # 4 p. 287 - 297 |
~% L-5-Hydroxytryp... CAS#:4350-09-8 |
Literature: Journal of Organic Chemistry, , vol. 22, p. 306,307 |
~% L-5-Hydroxytryp... CAS#:4350-09-8 |
Literature: Journal of Molecular Structure, , vol. 1045, p. 124 - 130 |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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The murine serotonin syndrome - evaluation of responses to 5-HT-enhancing drugs in NMRI mice.
Behav. Brain Res. 277 , 204-10, (2014) In humans, the ingestion of the combination of two or more serotonin (5-HT)-enhancing drugs but also of a single drug in overdose can induce serious adverse effects, which are characteristics of the s... |
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Substrate promiscuity of the cyclic dipeptide prenyltransferases from Aspergillus fumigatus ( section sign).
J. Nat. Prod. 72 , 44-52, (2009) This study reports that a series of tryptophan derivatives with modifications on the side chain or at the indole ring were accepted by two cyclic dipeptide prenyltransferases, CdpNPT and FtmPT1, and c... |
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