SB-399885

Modify Date: 2024-02-04 13:09:58

SB-399885 structure	Common Name	SB-399885
	CAS Number	402713-80-8	Molecular Weight	446.34800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₁Cl₂N₃O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SB-399885

SB399885 is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with pKi values 9.11 and 9.02 for human recombinant and native 5-HT6 receptors, respectively. SB399885 has cognitive enhancing properties[1].

Name	N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide,hydrochloride
Synonym	More Synonyms

Description	SB399885 is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with pKi values 9.11 and 9.02 for human recombinant and native 5-HT6 receptors, respectively. SB399885 has cognitive enhancing properties[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT6 Receptor:9.02 (pKi) Human 5-HT6 Receptor:9.11 (pKi)
References	[1]. Warren D Hirst, et al. SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models. Eur J Pharmacol. 2006 Dec 28;553(1-3):109-19.

Molecular Formula	C₁₈H₂₁Cl₂N₃O₄S
Molecular Weight	446.34800
Exact Mass	445.06300
PSA	88.28000
LogP	4.76860

N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(piperazin-1-yl)benzenesulfonamide

N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide

Benzenesulfonamide, N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)-

DC Chemicals Limited
China
Product Name: SB-399885 HCl
Price: $500.0/100mg $950.0/250mg $1900.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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