Methyl 2-chloro-6-picoline-4-carboxylate

Modify Date: 2024-01-03 01:26:34

Methyl 2-chloro-6-picoline-4-carboxylate Structure
Methyl 2-chloro-6-picoline-4-carboxylate structure
Common Name Methyl 2-chloro-6-picoline-4-carboxylate
CAS Number 3998-90-1 Molecular Weight 185.608
Density 1.2±0.1 g/cm3 Boiling Point 270.7±35.0 °C at 760 mmHg
Molecular Formula C8H8ClNO2 Melting Point 58-62ºC
MSDS Chinese USA Flash Point 117.5±25.9 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Names

Name Methyl 2-Chloro-6-methylpyridine-4-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 270.7±35.0 °C at 760 mmHg
Melting Point 58-62ºC
Molecular Formula C8H8ClNO2
Molecular Weight 185.608
Flash Point 117.5±25.9 °C
Exact Mass 185.024353
PSA 39.19000
LogP 2.08
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.528

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H315-H317-H318-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R37/38;R41;R43
Safety Phrases S26-S36/37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

 Synthetic Route

~98%

Methyl 2-chloro-6-picoline-4-carboxylate Structure

Methyl 2-chloro...

CAS#:3998-90-1

Literature: Zeneca Limited; Zeneca Pharma S.A., Patent: US5962458 A1, 1999 ; US 5962458 A

~%

Methyl 2-chloro-6-picoline-4-carboxylate Structure

Methyl 2-chloro...

CAS#:3998-90-1

Literature: DU PREEZ, Jan Gysbert Hermanus; WENTZEL, Mauritz; KNOETZE, Steyn Patent: WO2012/153253 A2, 2012 ; Location in patent: Page/Page column 67 ;

~90%

Methyl 2-chloro-6-picoline-4-carboxylate Structure

Methyl 2-chloro...

CAS#:3998-90-1

Literature: Havas, Fabien; Danel, Mathieu; Galaup, Chantal; Tisnes, Pierre; Picard, Claude Tetrahedron Letters, 2007 , vol. 48, # 6 p. 999 - 1002

~%

Methyl 2-chloro-6-picoline-4-carboxylate Structure

Methyl 2-chloro...

CAS#:3998-90-1

Literature: MERCK FROSST CANADA LTD. Patent: WO2008/46226 A1, 2008 ; Location in patent: Page/Page column 38; 39 ; WO 2008/046226 A1

~%

Methyl 2-chloro-6-picoline-4-carboxylate Structure

Methyl 2-chloro...

CAS#:3998-90-1

Literature: Sperber et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 704,707

~%

Methyl 2-chloro-6-picoline-4-carboxylate Structure

Methyl 2-chloro...

CAS#:3998-90-1

Literature: Dulla, Balakrishna; Wan, Baojie; Franzblau, Scott G.; Kapavarapu, Ravikumar; Reiser, Oliver; Iqbal, Javed; Pal, Manojit Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 14 p. 4629 - 4635

~%

Methyl 2-chloro-6-picoline-4-carboxylate Structure

Methyl 2-chloro...

CAS#:3998-90-1

Literature: Libermann et al. Bulletin de la Societe Chimique de France, 1958 , p. 687,691

~%

Methyl 2-chloro-6-picoline-4-carboxylate Structure

Methyl 2-chloro...

CAS#:3998-90-1

Literature: Havas, Fabien; Leygue, Nadine; Danel, Mathieu; Mestre, Beatrice; Galaup, Chantal; Picard, Claude Tetrahedron, 2009 , vol. 65, # 36 p. 7673 - 7686

~%

Methyl 2-chloro-6-picoline-4-carboxylate Structure

Methyl 2-chloro...

CAS#:3998-90-1

Literature: Libermann et al. Bulletin de la Societe Chimique de France, 1958 , p. 687,691

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2-Chloro-6-methylisonicotinic acid methyl ester
Methyl 2-chloro-6-methylisonicotinate
Methyl 2-chloro-6-picoline-4-carboxylate
4-Pyridinecarboxylic acid, 2-chloro-6-methyl-, methyl ester
2-Chloro-6-methyl-4-pyridinecarboxylic acid, methyl ester
T6NJ BG DVO1 F1
2-Chloro-6-methylpyridine-4-carboxylic Acid Methyl Ester
Methyl 2-chloro-6-methyl-4-pyridinecarboxylate
Methyl 2-chloro-6-methylpyridine-4-carboxylate
MFCD04038391