VRT-532
Modify Date: 2024-01-28 09:35:13
VRT-532 structure
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Common Name | VRT-532 | ||
|---|---|---|---|---|
| CAS Number | 38214-71-0 | Molecular Weight | 250.29500 | |
| Density | 1.213g/cm3 | Boiling Point | 472.9ºC at 760 mmHg | |
| Molecular Formula | C16H14N2O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 239.8ºC | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
Use of VRT-532VRT-532 (CFpot-532) is a potent is a potent CFTR modulator. VRT-532 enhances channel activity in G551D-CFTR and intrinsic ATPase activity of G551D-CFTR. VRT-532 has the potential for the research of cystic fibrosis[1][2]. |
| Name | 4-Methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol |
|---|---|
| Synonym | More Synonyms |
| Description | VRT-532 (CFpot-532) is a potent is a potent CFTR modulator. VRT-532 enhances channel activity in G551D-CFTR and intrinsic ATPase activity of G551D-CFTR. VRT-532 has the potential for the research of cystic fibrosis[1][2]. |
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| Related Catalog | |
| In Vitro | VRT-532 (15 µM) 直接结合重组的 G551D-CFTR 并改变其 ATP 酶活性[1]。 |
| References |
| Density | 1.213g/cm3 |
|---|---|
| Boiling Point | 472.9ºC at 760 mmHg |
| Molecular Formula | C16H14N2O |
| Molecular Weight | 250.29500 |
| Flash Point | 239.8ºC |
| Exact Mass | 250.11100 |
| PSA | 48.91000 |
| LogP | 3.75770 |
| Index of Refraction | 1.643 |
| Symbol |
GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
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VRT-532 CAS#:38214-71-0 |
| Literature: Agrawal, Nitin N.; Soni Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2007 , vol. 46, # 3 p. 532 - 534 |
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VRT-532 CAS#:38214-71-0 |
| Literature: Garcia, Heremengildo; Iborra, Sara; Miranda, Miguel A.; Morera, Isabel M.; Primo, Jaime Heterocycles, 1991 , vol. 32, # 9 p. 1745 - 1755 |
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VRT-532 CAS#:38214-71-0 |
| Literature: Reddy, N. J.; Sharma, T. C. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 715 - 718 |
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VRT-532 CAS#:38214-71-0 |
| Literature: Alkhouri, Bashar; Denning, Robert A.; Chiaw, Patrick Kim; Eckford, Paul D.W.; Yu, Wilson; Li, Canhui; Bogojeski, Jovanka J.; Bear, Christine E.; Viirre, Russell D. Journal of Medicinal Chemistry, 2011 , vol. 54, # 24 p. 8693 - 8701 |
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VRT-532 CAS#:38214-71-0 |
| Literature: Alkhouri, Bashar; Denning, Robert A.; Chiaw, Patrick Kim; Eckford, Paul D.W.; Yu, Wilson; Li, Canhui; Bogojeski, Jovanka J.; Bear, Christine E.; Viirre, Russell D. Journal of Medicinal Chemistry, 2011 , vol. 54, # 24 p. 8693 - 8701 |
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VRT-532 CAS#:38214-71-0 |
| Literature: Alkhouri, Bashar; Denning, Robert A.; Chiaw, Patrick Kim; Eckford, Paul D.W.; Yu, Wilson; Li, Canhui; Bogojeski, Jovanka J.; Bear, Christine E.; Viirre, Russell D. Journal of Medicinal Chemistry, 2011 , vol. 54, # 24 p. 8693 - 8701 |
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VRT-532 CAS#:38214-71-0 |
| Literature: Sharma, T. C.; Bokadia, M. M.; Reddy, N. J. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 3 p. 228 - 229 |
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VRT-532 CAS#:38214-71-0 |
| Literature: Sharma, T. C.; Bokadia, M. M.; Reddy, N. J. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 3 p. 228 - 229 |
| 4-heptyl-2-(1(2)H-tetrazol-5-yl)-phenol |
| Phenol,4-heptyl-2-(1H-tetrazol-5-yl) |
| 5-(2-hydroxy-5-methylphenyl)-3-phenylpyrazole |
| 5-(2-hydroxy-5-heptylphenyl)tetrazole |
| 3-(2-hydroxy-5-methylphenyl)-5-phenylpyrazole |
| 5-(2-Hydroxy-5-heptylphenyl)tetrazol |