CMPDA
Modify Date: 2024-01-02 18:26:11
CMPDA structure
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Common Name | CMPDA | ||
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| CAS Number | 380607-77-2 | Molecular Weight | 376.53500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H28N2O4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CMPDACMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ± 4.2 nM/63.4 ± 5.6 nM for GluA2i/GluA2o receptor.IC50 value: 45.4 ± 4.2 nM/63.4 ± 5.6 nM(GluA2i/GluA2o) [1]Target: AMPAR modulatorCMPDA was nearly equipotent at modulating the two isoforms of GluA2 receptors, whereas CMPDB displayed a modest preference for the flip splice variant. Similar to CX614, CMPDA slowed the rate of deactivation of GluA2o receptors approximately 2-fold but had no effect on GluA2i receptor deactivation [1]. |
| Name | [(methylethyl)sulfonyl]{2-[4-(2-{[(methylethyl)sulfonyl]amino}ethyl)phenyl]ethyl}amine |
|---|---|
| Synonym | More Synonyms |
| Description | CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ± 4.2 nM/63.4 ± 5.6 nM for GluA2i/GluA2o receptor.IC50 value: 45.4 ± 4.2 nM/63.4 ± 5.6 nM(GluA2i/GluA2o) [1]Target: AMPAR modulatorCMPDA was nearly equipotent at modulating the two isoforms of GluA2 receptors, whereas CMPDB displayed a modest preference for the flip splice variant. Similar to CX614, CMPDA slowed the rate of deactivation of GluA2o receptors approximately 2-fold but had no effect on GluA2i receptor deactivation [1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C16H28N2O4S2 |
|---|---|
| Molecular Weight | 376.53500 |
| Exact Mass | 376.14900 |
| PSA | 109.10000 |
| LogP | 4.37060 |
| Storage condition | 2-8℃ |
| sch 529074 |
| CMPDA |