3-fluoroaniline

Modify Date: 2024-01-02 11:23:25

3-fluoroaniline Structure
3-fluoroaniline structure
Common Name 3-fluoroaniline
CAS Number 372-19-0 Molecular Weight 111.117
Density 1.2±0.1 g/cm3 Boiling Point 186.3±13.0 °C at 760 mmHg
Molecular Formula C6H6FN Melting Point -2°C
MSDS Chinese USA Flash Point 77.2±0.0 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Names

Name 3-fluoroaniline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 186.3±13.0 °C at 760 mmHg
Melting Point -2°C
Molecular Formula C6H6FN
Molecular Weight 111.117
Flash Point 77.2±0.0 °C
Exact Mass 111.048424
PSA 26.02000
LogP 1.39
Vapour Pressure 0.7±0.4 mmHg at 25°C
Index of Refraction 1.548
Water Solubility insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BY1400000
CHEMICAL NAME :
Aniline, 3-fluoro-
CAS REGISTRY NUMBER :
372-19-0
BEILSTEIN REFERENCE NO. :
1305471
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H6-F-N
MOLECULAR WEIGHT :
111.13
WISWESSER LINE NOTATION :
ZR CF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H315-H318-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R36/38
Safety Phrases S26-S36/39-S37/39
RIDADR UN 2941 6.1/PG 3
WGK Germany 3
RTECS BY1400000
Packaging Group III
Hazard Class 6.1
HS Code 29214210

 Synthetic Route

 Customs

HS Code 2921420090
Summary HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles3

More Articles
cIEF for rapid pKa determination of small molecules: a proof of concept.

Eur. J. Pharm. Sci. 63 , 14-21, (2014)

A capillary isoelectric focusing (cIEF) method was developed for the determination of the ionization constants (pKa) of small molecules. Two approaches used to decrease the electroosmotic flow (EOF) w...

The many roles for fluorine in medicinal chemistry.

J. Med. Chem. 51 , 4359-69, (2008)

Study on the regioselectivity and mechanism of the aromatic hydroxylation of monofluoroanilines.

Chem. Biol. Interact. 85(2-3) , 151-72, (1992)

The in vitro and in vivo metabolism of monofluoroanilines was investigated. Special attention was focused on the regioselectivity of the aromatic hydroxylation by cytochromes P-450 and the mechanism b...

 Synonyms

Benzenamine, 3-fluoro-
3-Fluoranilin
3-Fluoroaniline
Aniline,m-fluoro
Aniline,3-fluoro
3-FLUORO-PHENYLAMINE
3-Fluorobenzenamine
p-fluoroaniline
m-fluoro aniline
MFCD00007758
3-fluoro-aniline
3-fluoro-anilin
EINECS 206-747-0
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