N6-Cyclohexyladenosine

Modify Date: 2024-01-02 20:17:12

N6-Cyclohexyladenosine Structure
N6-Cyclohexyladenosine structure
Common Name N6-Cyclohexyladenosine
CAS Number 36396-99-3 Molecular Weight 349.38500
Density 1.71g/cm3 Boiling Point 675.2ºC at 760mmHg
Molecular Formula C16H23N5O4 Melting Point N/A
MSDS Chinese USA Flash Point 362.1ºC

 Use of N6-Cyclohexyladenosine


N6-Cyclohexyladenosine is a selective A1 receptor agonist (EC50 = 8.2 nM). IC50 value: 8.2 nM (EC50)Target: A1 receptorin vivo: N6-Cyclohexyladenosine exerts anticonvulsant effects and protects against neuronal death. CHA was also found to inhibit the pressor effects of lumbar sympathetic nerve stimulation in rats.

 Names

Name (2R,3R,4S,5R)-2-(6-(Cyclohexylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Synonym More Synonyms

 N6-Cyclohexyladenosine Biological Activity

Description N6-Cyclohexyladenosine is a selective A1 receptor agonist (EC50 = 8.2 nM). IC50 value: 8.2 nM (EC50)Target: A1 receptorin vivo: N6-Cyclohexyladenosine exerts anticonvulsant effects and protects against neuronal death. CHA was also found to inhibit the pressor effects of lumbar sympathetic nerve stimulation in rats.
Related Catalog
References

[1]. Asghari AA, et al. Adenosine A1 receptor agonist, N6-cyclohexyladenosine, protects myelin and induces remyelination in an experimental model of rat optic chiasm demyelination; electrophysiological and histopathological studies. J Neurol Sci. 2013 Feb 15;3

 Chemical & Physical Properties

Density 1.71g/cm3
Boiling Point 675.2ºC at 760mmHg
Molecular Formula C16H23N5O4
Molecular Weight 349.38500
Flash Point 362.1ºC
Exact Mass 349.17500
PSA 125.55000
LogP 0.25540
Index of Refraction 1.787
Storage condition 2-8℃

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles34

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 Synonyms

N6-Cyclohexyladenosine