5-Amino-4-imidazolecarboxamide

Modify Date: 2024-01-02 14:31:04

5-Amino-4-imidazolecarboxamide structure	Common Name	5-Amino-4-imidazolecarboxamide
	CAS Number	360-97-4	Molecular Weight	126.117
	Density	1.8±0.1 g/cm3	Boiling Point	535.4±60.0 °C at 760 mmHg
	Molecular Formula	C₄H₆N₄O	Melting Point	164-170 °C(lit.)
	MSDS	Chinese USA	Flash Point	277.6±32.9 °C
	Symbol	GHS07	Signal Word	Warning

Use of 5-Amino-4-imidazolecarboxamide

5-Amino-3H-imidazole-4-Carboxamide (AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular.

Name	5-Amino-4-imidazolecarboxamide
Synonym	More Synonyms

Description	5-Amino-3H-imidazole-4-Carboxamide (AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular.
Related Catalog	Natural Products >> Others Research Areas >> Others
Target	Human Endogenous Metabolite
References	[1]. YANG LIU. VARIABLE-TEMPERATURE 1 H-NMR AND AB INITIO STUDY OF 5-AMINO-IMIDAZOLE-4-CARBOXAMIDE (AICA): COMPETING PATHS FOR AMIDE-H SCRAMBLING. DECEMBER 2008.

Density	1.8±0.1 g/cm3
Boiling Point	535.4±60.0 °C at 760 mmHg
Melting Point	164-170 °C(lit.)
Molecular Formula	C₄H₆N₄O
Molecular Weight	126.117
Flash Point	277.6±32.9 °C
Exact Mass	126.054161
PSA	97.79000
LogP	-1.01
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.799

5-Amino-4-imidazolecarboxamide MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI3910000

CHEMICAL NAME :: Imidazole-4-carboxamide, 5-amino-

CAS REGISTRY NUMBER :: 360-97-4

LAST UPDATED :: 199806

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C4-H6-N4-O

MOLECULAR WEIGHT :: 126.14

WISWESSER LINE NOTATION :: T5M CNJ DVZ EZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 22750 mg/kg/13W-I

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in adrenal weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 2275 mg/kg/13W-I

TOXIC EFFECTS :: Gastrointestinal - nausea or vomiting Endocrine - changes in thymus weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6390 mg/kg/21W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - rat Cells - not otherwise specified

DOSE/DURATION :: 3 mmol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 36,2827,1976

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	NI3910000
HS Code	2934999090

Precursor 9
CAS#:85623-02-5 3-benzyl-4-oxoi... CAS#:76055-09-9 4(5)-oxoimidazo... CAS#:2627-69-2 Acadesine (AICAR) CAS#:37842-62-9 Methanimidic ac...
CAS#:85622-95-3 Imidazo[5,1-d]-... CAS#:100191-43-3 3-Amino-2-(form... CAS#:6313-33-3 Formimidamide h... CAS#:6719-21-7 3-Nitriloalaninamide
CAS#:7664-93-9 Sulfuric acid
DownStream 10
CAS#:4656-86-4 2-Azahypoxanthine CAS#:1998-63-6 6-chloro-2-(tri... CAS#:72-40-2 5-Amino-1H-imid... CAS#:7008-85-7 5-Diazoimidazol...
CAS#:3031-94-5 Aica ribonucleotide CAS#:85622-95-3 Imidazo[5,1-d]-... CAS#:69-89-6 2,6-Dihydroxypurine CAS#:101752-15-2 2-oxo-3,4-dihyd...
CAS#:10333-86-5 4-(benzoylcarba... CAS#:21190-16-9 Ethyl 4-amino-1...

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Differential effects of AMPK agonists on cell growth and metabolism.

Oncogene 34 , 3627-39, (2015)

As a sensor of cellular energy status, the AMP-activated protein kinase (AMPK) is believed to act in opposition to the metabolic phenotypes favored by proliferating tumor cells. Consequently, compound...

Short-chain fatty acids enhance adipocyte differentiation in the stromal vascular fraction of porcine adipose tissue.

J. Nutr. 144(12) , 1887-95, (2014)

Short-chain fatty acids (SCFAs), including acetate, propionate, and butyrate, are the main products of microbial fermentation in the gut and might mediate some of the effects of gut microbiota and nut...

Molecular characterization, fitness and mycotoxin production of benzimidazole-resistant isolates of Penicillium expansum.

Int. J. Food Microbiol. 162(3) , 237-44, (2013)

Penicillium expansum field-strains resistant to benzimidazole fungicides were isolated in high frequency from decayed apple fruit collected from packinghouses and processing industries located in the ...

4-AMino-5-carbaMoyliMidazole

4(5)-aminoimidazole-5(4)-carboxamide

5-aminoimidazole-4-carboxamide

diazol-c

5-amino-4-imidazole carboxamide

4-Amino-5-imidazolecarboxamide

T5M CNJ DVZ EZ

MFCD02181040

EINECS 206-641-4

4-aminoimidazole-5-carboxamide

ba2756

1H-Imidazole-4-carboxamide, 5-amino-

5-Amino-4-imidazolecarboxamide

aminoimidazolecarboxamide

4-amino-5-imidazolecarboxamid

4-Amino-5-imodazole

aic

4-Aminoimidzole-5-carboxamide

5-Amino-Imidazole-4-carboxamide

5-amino-1H-imidazole-4-carboxamide

4-Amino-1H-imidazole-5-carboxamide

T5M CNJ DZ EVZ

1H-Imidazole-4-carboximidic acid, 5-amino-

5-AMINO-1H-IMIDAZOLE 4-CARBOXAMIDE

Dacarbazine Impurity 2

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 5-Amino-4-imidazolecarboxamide
Price: ￥268.0/25g ￥88.0/5g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-Amino-4-imidazolecarboxamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 5-Amino-4-imidazolecarboxamide
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 5-Amino-4-imidazolecarboxamide
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

Get all suppliers and price by the below link:

5-Amino-4-imidazolecarboxamide suppliers

Price: ￥70/5g

Reference only. check more 5-Amino-4-imidazolecarboxamide price

5-Amino-4-imidazolecarboxamide

Use of 5-Amino-4-imidazolecarboxamide

Names