ethyl heptafluorobutyrate

Modify Date: 2024-01-11 17:28:13

ethyl heptafluorobutyrate Structure
ethyl heptafluorobutyrate structure
Common Name ethyl heptafluorobutyrate
CAS Number 356-27-4 Molecular Weight 242.09200
Density 1.396 g/mL at 25 °C(lit.) Boiling Point 95-98°C
Molecular Formula C6H5F7O2 Melting Point N/A
MSDS USA Flash Point 58 °F
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Names

Name ethyl 2,2,3,3,4,4,4-heptafluorobutanoate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.396 g/mL at 25 °C(lit.)
Boiling Point 95-98°C
Molecular Formula C6H5F7O2
Molecular Weight 242.09200
Flash Point 58 °F
Exact Mass 242.01800
PSA 26.30000
LogP 2.38240
Index of Refraction n20/D 1.302(lit.)
Storage condition Flammables area

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ET4200000
CHEMICAL NAME :
Butyric acid, heptafluoro-, ethyl ester
CAS REGISTRY NUMBER :
356-27-4
BEILSTEIN REFERENCE NO. :
1794634
LAST UPDATED :
199709
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C6-H5-F7-O2
MOLECULAR WEIGHT :
242.11
WISWESSER LINE NOTATION :
FXFFXFFXFFVO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 2,299,1950 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4670 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H315-H319-H335
Precautionary Statements P210-P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F: Flammable;Xi: Irritant;
Risk Phrases R10
Safety Phrases S16-S26-S33-S36
RIDADR UN 3272 3/PG 2
WGK Germany 3
RTECS ET4200000
Packaging Group II
Hazard Class 3
HS Code 2915900090

 Synthetic Route

~%

ethyl heptafluorobutyrate Structure

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CAS#:356-27-4

Literature: Journal of the Chemical Society, , p. 2789,2791 Journal of Organic Chemistry, , vol. 23, p. 476 Journal of the American Chemical Society, , vol. 75, p. 992 Journal of the American Chemical Society, , vol. 77, p. 4164,4167

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ethyl heptafluorobutyrate Structure

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CAS#:356-27-4

Literature: Journal of the American Chemical Society, , vol. 79, p. 4759

~94%

ethyl heptafluorobutyrate Structure

ethyl heptafluo...

CAS#:356-27-4

Literature: Avetisyan; Cherstkov; Tumanskii; Sterlin Russian Chemical Bulletin, 1998 , vol. 47, # 12 p. 2429 - 2433

~%

ethyl heptafluorobutyrate Structure

ethyl heptafluo...

CAS#:356-27-4

Literature: Zh. Vses. Khim. Obshchestva, , vol. 26, p. 34718 C.A., , vol. 95, p. 168460

~%

ethyl heptafluorobutyrate Structure

ethyl heptafluo...

CAS#:356-27-4

Literature: Russian Chemical Bulletin, , vol. 47, # 12 p. 2429 - 2433

 Customs

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

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PLoS ONE 5 , e13277, (2010)

Diagnosis of chronic intestinal inflammation, which characterizes inflammatory bowel disease (IBD), along with prediction of disease state is hindered by the availability of predictive serum biomarker...

The Reaction of Ethyl Perfluorobutyrate with Sodium. An Improved Synthesis of Perfluoroheptan-4-one. Hauptschein M and Braun RA.

J. Am. Chem. Soc. 77(18) , 4930-4931, (1955)

 Synonyms

Ethyl heptafluorobutanoate
Ethyl heptafluorobutyrate
Perfluorobutyric Acid Ethyl Ester
2,2,3,3,4,4,4-heptafluoro-butyric acid ethyl ester
EINECS 206-602-1
ethyl perfluoroisobutyrate
Butanoic acid,heptafluoro-,ethyl ester
BUTYRIC ACID,HEPTAFLUORO-,ETHYL ESTER
Ethyl Perfluorobutyrate
Heptafluorobutyric acid ethyl ester
ethyl 2,2,3,3,4,4,4-heptafluorobutyrate
Ethyl perfluorobutanoate
MFCD00000434