Silicristin
Silicristin structure
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Common Name | Silicristin | ||
|---|---|---|---|---|
| CAS Number | 33889-69-9 | Molecular Weight | 482.436 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 782.0±60.0 °C at 760 mmHg | |
| Molecular Formula | C25H22O10 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 270.5±26.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of SilicristinSilychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2]. |
| Name | silychristin |
|---|---|
| Synonym | More Synonyms |
| Description | Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 782.0±60.0 °C at 760 mmHg |
| Molecular Formula | C25H22O10 |
| Molecular Weight | 482.436 |
| Flash Point | 270.5±26.4 °C |
| Exact Mass | 482.121307 |
| PSA | 166.14000 |
| LogP | 2.20 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.716 |
| Storage condition | 2-8°C |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
CAS#:1835-11-6
CAS#:124662-51-7
CAS#:16414-34-9|
Effect of the flavanolignans of Silybum marianum L. on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes.
Pharmacol. Res. 25(2) , 147-54, (1992) The effect of several flavanolignans (silicristin, silidianin, silybin and isosilybin) present in silymarin, the extract of Silybum marianum fruits, was tested on lipid peroxidation in rat liver micro... |
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Separation and characterization of silybin, isosilybin, silydianin and silychristin in milk thistle extract by liquid chromatography-electrospray tandem mass spectrometry.
J. Chromatogr. A. 1116(1-2) , 57-68, (2006) A selective and sensitive liquid chromatography/tandem mass spectrometry (LC/MS/MS) method has been developed for the characterization of silymarin in commercially available milk thistle extract. In t... |
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Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells.
Int. J. Cancer 123(1) , 41-50, (2008) Prostate cancer (PCa) is the leading cause of cancer-related deaths in men; urgent measures are warranted to lower this deadly malignancy. Silymarin is a known cancer chemopreventive agent, but the re... |
| Silicristin |
| EINECS 251-720-9 |
| Silicristinum |
| (2R,3R)-3,5,7-trihydroxy-2-[(2R,3S)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1-benzofuran-5-yl]-2,3-dihydrochromen-4-one |
| Silicristinum [INN-Latin] |
| Silicristina |
| (2R,3R)-3,5,7-Trihydroxy-2-[(2R,3S)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1-benzofuran-5-yl]-2,3-dihydro-4H-chromen-4-one |
| Silicristina [INN-Spanish] |
| 4H-1-Benzopyran-4-one, 2-[(2R,3S)-2,3-dihydro-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-benzofuranyl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)- |
| Silychristin |
| Silymarin II |
| Silicristine [INN-French] |
| (2R,3R)-3,5,7-trihydroxy-2-[(2R,3S)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-hydroxymethyl-2,3-dihydrobenzofuran-5-yl]chroman-4-one |
| Silicristine |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Silicristin
- Price: ￥2748.0/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
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