3-Amino-4-phenylbutyric acid hydrochloride

Modify Date: 2024-01-09 18:12:54

3-Amino-4-phenylbutyric acid hydrochloride Structure
3-Amino-4-phenylbutyric acid hydrochloride structure
Common Name 3-Amino-4-phenylbutyric acid hydrochloride
CAS Number 3060-41-1 Molecular Weight 215.677
Density 1.161g/cm3 Boiling Point 327.8ºC at 760 mmHg
Molecular Formula C10H14ClNO2 Melting Point 194-201ºC
MSDS N/A Flash Point 152.1ºC

 Use of 3-Amino-4-phenylbutyric acid hydrochloride


Phenibut (β-Phenyl-GABA) hydrochloride is an orally active GABA-B agonist[1]. Phenibut hydrochloride acts as a GABA-mimetic, primarily at GABAB receptors. Phenibut hydrochloride has anxiolytic and nootropic (cognition enhancing) effects[2].

 Names

Name 3-Amino-4-phenylbutyric acid hydrochloride
Synonym More Synonyms

  Biological Activity

Description Phenibut (β-Phenyl-GABA) hydrochloride is an orally active GABA-B agonist[1]. Phenibut hydrochloride acts as a GABA-mimetic, primarily at GABAB receptors. Phenibut hydrochloride has anxiolytic and nootropic (cognition enhancing) effects[2].
Related Catalog
Target

GABA-B[1][2]

In Vitro Phenibut hydrochloride is a neuropsychotropic agent. Phenibut hydrochloride also stimulates dopamine receptors and antagonizes β-phenethylamine (PEA), a putative endogenous anxiogenic[2].
References

[1]. Ahuja T, et al. Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: EmergingNootropics of Abuse. Case Rep Psychiatry. 2018 Apr 30;2018:9864285.

[2]. Lapin I. Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS Drug Rev. 2001 Winter;7(4):471-81.

 Chemical & Physical Properties

Density 1.161g/cm3
Boiling Point 327.8ºC at 760 mmHg
Melting Point 194-201ºC
Molecular Formula C10H14ClNO2
Molecular Weight 215.677
Flash Point 152.1ºC
Exact Mass 215.071304
PSA 63.32000
LogP 2.53340

 Safety Information

Hazard Codes Xi
HS Code 2922499990

 Synthetic Route

~%

3-Amino-4-phenylbutyric acid hydrochloride Structure

3-Amino-4-pheny...

CAS#:3060-41-1

Literature: Kreile, D. R.; Slavinskaya, V. A.; Ziemelis, K. M.; Tomsons, U. A.; Gutmanis, A. E.; et al. J. Appl. Chem. USSR (Engl. Transl.), 1982 , vol. 55, # 4 p. 972 - 974,902 - 904

~55%

3-Amino-4-phenylbutyric acid hydrochloride Structure

3-Amino-4-pheny...

CAS#:3060-41-1

Literature: Biswas, Kallolmay; Gholap, Rajesh; Srinivas, Padakanti; Kanyal, Sachin; Sarma, Koushik Das RSC Advances, 2014 , vol. 4, # 5 p. 2538 - 2545

~%

3-Amino-4-phenylbutyric acid hydrochloride Structure

3-Amino-4-pheny...

CAS#:3060-41-1

Literature: RSC Advances, , vol. 4, # 5 p. 2538 - 2545

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Synonyms

4-Amino-3-phenylbutanoic acid hydrochloride
PHENIBUT
4-Amino-3-phenyl-buttersaeure,Hydrochlorid
3-AMINO-4-PHENYLBUTYRIC ACID HCL
MFCD00456233
3-Amino-4-phenylbutanoic acid hydrochloride (1:1)
FENIBUT
4-amino-3-phenyl-butyric acid,hydrochloride
Benzenebutanoic acid, β-amino-, hydrochloride (1:1)
4-AMINO-3-PHENYL-BUTYRIC ACID
4-AMINO-3-PHENYLBUTIRIC ACID
Phenibut(4-Amino-3-Phenylbutanoic Acid HCl)