Carphenazine Dimaleate

Modify Date: 2024-01-02 17:44:45

Carphenazine Dimaleate Structure
Carphenazine Dimaleate structure
Common Name Carphenazine Dimaleate
CAS Number 2975-34-0 Molecular Weight 541.65900
Density N/A Boiling Point 616.9ºC at 760 mmHg
Molecular Formula C28H35N3O6S Melting Point N/A
MSDS N/A Flash Point 326.9ºC

 Use of Carphenazine Dimaleate


Carphenazine dimaleate is an antipsychotic agent, mainly used for the treatment of chronic schizophrenia.

 Names

Name carphenazine maleate
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 616.9ºC at 760 mmHg
Molecular Formula C28H35N3O6S
Molecular Weight 541.65900
Flash Point 326.9ºC
Exact Mass 541.22500
PSA 146.92000
LogP 3.53460
Vapour Pressure 4.46E-16mmHg at 25°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UC2975000
CAS REGISTRY NUMBER :
2975-34-0
LAST UPDATED :
199707
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C24-H31-N3-O2-S.2C4-H4-O4
MOLECULAR WEIGHT :
657.80
WISWESSER LINE NOTATION :
T C666 BN ISJ EV2 B3- AT6N DNTJ D2Q &OV1U1VO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
162 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,12,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
89 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,12,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
156 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,12,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
88 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,12,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,12,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
42 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,12,1972

 Synonyms

Proketazine
Proketazine dimaleate
(Z)-but-2-enedioic acid,1-[10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazin-2-yl]propan-1-one
Carphenazine dimaleate
EINECS 221-019-2
CARPHENAZINE MALEATE
Carfenazine hydrogen maleate
Procethazine dimaleate
Proketazine maleate
Carfenazine maleate