γ-Secretase modulator 11
Modify Date: 2024-01-09 14:33:33
γ-Secretase modulator 11 structure
|
Common Name | γ-Secretase modulator 11 | ||
|---|---|---|---|---|
| CAS Number | 2434630-29-0 | Molecular Weight | 484.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H22F2N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of γ-Secretase modulator 115-{8-[(3,4'- difluoro [1,1'- biphenyl]-4-yl) methoxy] - 2-methylimidazo [1,2-a] pyridin-3-yl}-n-methylpyridin-2-formamide (1o) showed high potency in vitro and brain exposure, inducing brain a β 42 levels were significantly reduced and showed undetectable inhibition of cytochrome P450 enzymes. In addition, compound 1o showed excellent anti cognitive deficit effect in AD model mice. |
| Name | γ-Secretase modulator 11 |
|---|
| Description | 5-{8-[(3,4'- difluoro [1,1'- biphenyl]-4-yl) methoxy] - 2-methylimidazo [1,2-a] pyridin-3-yl}-n-methylpyridin-2-formamide (1o) showed high potency in vitro and brain exposure, inducing brain a β 42 levels were significantly reduced and showed undetectable inhibition of cytochrome P450 enzymes. In addition, compound 1o showed excellent anti cognitive deficit effect in AD model mice. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C28H22F2N4O2 |
|---|---|
| Molecular Weight | 484.50 |