6-Methoxy-1,5-naphthyridin-4-ol

Modify Date: 2024-01-08 18:19:55

6-Methoxy-1,5-naphthyridin-4-ol Structure
6-Methoxy-1,5-naphthyridin-4-ol structure
Common Name 6-Methoxy-1,5-naphthyridin-4-ol
CAS Number 23443-25-6 Molecular Weight 176.172
Density 1.3±0.1 g/cm3 Boiling Point 339.6±37.0 °C at 760 mmHg
Molecular Formula C9H8N2O2 Melting Point N/A
MSDS N/A Flash Point 159.2±26.5 °C

 Names

Name 6-methoxy-1H-1,5-naphthyridin-4-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 339.6±37.0 °C at 760 mmHg
Molecular Formula C9H8N2O2
Molecular Weight 176.172
Flash Point 159.2±26.5 °C
Exact Mass 176.058578
PSA 54.98000
LogP 1.78
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.659

 Safety Information

Hazard Codes Xn
HS Code 2933990090

 Synthetic Route

~86%

6-Methoxy-1,5-naphthyridin-4-ol Structure

6-Methoxy-1,5-n...

CAS#:23443-25-6

Literature: Gomez, Laurent; Hack, Michael D.; Wu, Jiejun; Wiener, John J.M.; Venkatesan, Hari; Santillan Jr., Alejandro; Pippel, Daniel J.; Mani, Neelakandha; Morrow, Brian J.; Motley, S. Timothy; Shaw, Karen Joy; Wolin, Ronald; Grice, Cheryl A.; Jones, Todd K. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 10 p. 2723 - 2727

~70%

6-Methoxy-1,5-naphthyridin-4-ol Structure

6-Methoxy-1,5-n...

CAS#:23443-25-6

Literature: SMITHKLINE BEECHAM P.L.C. Patent: WO2003/87098 A1, 2003 ; Location in patent: Page/Page column 37 ;

~68%

6-Methoxy-1,5-naphthyridin-4-ol Structure

6-Methoxy-1,5-n...

CAS#:23443-25-6

Literature: Davies, David Thomas; Markwell, Roger Edward; Pearson, Neil David Patent: US2004/53928 A1, 2004 ;

~34%

6-Methoxy-1,5-naphthyridin-4-ol Structure

6-Methoxy-1,5-n...

CAS#:23443-25-6

Literature: SIRTRIS PHARMACEUTICALS, INC.; VU, Chi, B.; CASAUBON, Rebecca, L. Patent: WO2010/101949 A1, 2010 ; Location in patent: Page/Page column 125 ; WO 2010/101949 A1

~68%

6-Methoxy-1,5-naphthyridin-4-ol Structure

6-Methoxy-1,5-n...

CAS#:23443-25-6

Literature: GLAXO GROUP LIMITED Patent: WO2006/20561 A2, 2006 ; Location in patent: Page/Page column 29 ;

~%

6-Methoxy-1,5-naphthyridin-4-ol Structure

6-Methoxy-1,5-n...

CAS#:23443-25-6

Literature: MORPHOCHEM AKTIENGESELLSCHAFT FUeR KOMBINATORISCHE CHEMIE Patent: WO2006/21448 A1, 2006 ; Location in patent: Page/Page column 28 ;

~%

6-Methoxy-1,5-naphthyridin-4-ol Structure

6-Methoxy-1,5-n...

CAS#:23443-25-6

Literature: SMITHKLINE BEECHAM PLC Patent: EP1214314 B1, 2005 ; Location in patent: Page/Page column 15 ;

~%

6-Methoxy-1,5-naphthyridin-4-ol Structure

6-Methoxy-1,5-n...

CAS#:23443-25-6

Literature: KYORIN PHARMACEUTICAL CO., LTD.; MERCK SHARP and DOHME CORP.; FUKUDA, Yasumichi; KAELIN, David E. Jr.; SINGH, Sheo B. Patent: WO2013/3383 A1, 2013 ;

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

6-Methoxy-1,5-naphthyridin-4-ol
6-methoxy-1,5-naphthyridine-4-ol
6-methoxy-1H-[1,5]naphthyridin-4-one
4-hydroxy-6-methoxy-[1,5]naphthyridine
1,5-Naphthyridin-4-ol, 6-methoxy-
6-(methyloxy)-1,5-naphthyridin-4-ol
1,5-Naphthyridin-4-ol,6-methoxy