Amine-PEG3-Desthiobiotin

Modify Date: 2024-01-08 09:52:24

Amine-PEG3-Desthiobiotin Structure
Amine-PEG3-Desthiobiotin structure
Common Name Amine-PEG3-Desthiobiotin
CAS Number 2237234-71-6 Molecular Weight 388.50
Density N/A Boiling Point N/A
Molecular Formula C18H36N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amine-PEG3-Desthiobiotin


Amine-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Amine-PEG3-Desthiobiotin

 Amine-PEG3-Desthiobiotin Biological Activity

Description Amine-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H36N4O5
Molecular Weight 388.50