Miconazole-d2

Modify Date: 2024-01-07 11:52:20

Miconazole-d2 Structure
Miconazole-d2 structure
Common Name Miconazole-d2
CAS Number 2140316-33-0 Molecular Weight 418.14
Density N/A Boiling Point N/A
Molecular Formula C18H12D2Cl4N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Miconazole-d2


Miconazole-d2 is the deuterium labeled Miconazole[1]. Miconazole (R18134) is an imidazole antifungal agent. Miconazole also has antibacterial effects[2][3].

 Names

Name Miconazole-d2

 Miconazole-d2 Biological Activity

Description Miconazole-d2 is the deuterium labeled Miconazole[1]. Miconazole (R18134) is an imidazole antifungal agent. Miconazole also has antibacterial effects[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. http://en.wikipedia.org/wiki/Miconazole

[3]. Nenoff P, et al. New insights on the antibacterial efficacy of miconazole in vitro. Mycoses. 2017 Aug;60(8):552-557.  

 Chemical & Physical Properties

Molecular Formula C18H12D2Cl4N2O
Molecular Weight 418.14