N4-Acetylsulfamethoxazole
Modify Date: 2024-01-11 18:07:28
N4-Acetylsulfamethoxazole structure
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Common Name | N4-Acetylsulfamethoxazole | ||
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| CAS Number | 21312-10-7 | Molecular Weight | 295.31400 | |
| Density | 1.448g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C12H13N3O4S | Melting Point | 222ºC dec. | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of N4-AcetylsulfamethoxazoleN4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) is a metabolite of Sulfamethoxazole (HY-B0322). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic, used for bacterial infections[1]. |
| Name | N-acetylsulfamethoxazole |
|---|---|
| Synonym | More Synonyms |
| Description | N4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) is a metabolite of Sulfamethoxazole (HY-B0322). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic, used for bacterial infections[1]. |
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| Related Catalog | |
| References |
[1]. https://pubchem.ncbi.nlm.nih.gov/compound/Acetylsulfamethoxazole |
| Density | 1.448g/cm3 |
|---|---|
| Melting Point | 222ºC dec. |
| Molecular Formula | C12H13N3O4S |
| Molecular Weight | 295.31400 |
| Exact Mass | 295.06300 |
| PSA | 109.68000 |
| LogP | 2.96900 |
| Index of Refraction | 1.622 |
| Storage condition | Refrigerator |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| RIDADR | NONH for all modes of transport |
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| HS Code | 2935009090 |
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~80%
N4-Acetylsulfam... CAS#:21312-10-7 |
| Literature: Brimacombe, Kyle R.; Walsh, Martin J.; Liu, Li; Vasquez-Valdivieso, Montserrat G.; Morgan, Hugh P.; McNae, Iain; Fothergill-Gilmore, Linda A.; Michels, Paul A. M.; Auld, Douglas S.; Simeonov, Anton; Walkinshaw, Malcolm D.; Shen, Min; Boxer, Matthew B. ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 1 p. 12 - 17 |
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~71%
N4-Acetylsulfam... CAS#:21312-10-7 |
| Literature: Wang, Gong-Bao; Wang, Lin-Fa; Li, Chao-Zhang; Sun, Jing; Zhou, Guang-Ming; Yang, Da-Cheng Research on Chemical Intermediates, 2012 , vol. 38, # 1 p. 77 - 89 |
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N4-Acetylsulfam... CAS#:21312-10-7 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 10, p. 572 - 575 |
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N4-Acetylsulfam... CAS#:21312-10-7 |
| Literature: Chemosphere, , vol. 57, # 11 p. 1733 - 1738 |
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N4-Acetylsulfam... CAS#:21312-10-7 |
| Literature: Journal of Pharmacology and Experimental Therapeutics, , vol. 274, # 3 p. 1099 - 1104 |
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N4-Acetylsulfam... CAS#:21312-10-7 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 10, p. 572 - 575 |
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~%
N4-Acetylsulfam... CAS#:21312-10-7 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 10, p. 572 - 575 |
|
~%
N4-Acetylsulfam... CAS#:21312-10-7 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 10, p. 572 - 575 |
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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Excretion rates of sulfamethoxazole and N4-acetyl-sulfamethoxazole by fresh water turtles Pseudemys scripta elegans.
Vet. Q. 6(3) , 169-73, (1984) Sulfamethoxazole and N4-acetylsulfamethoxazole are excreted by fresh water turtles Pseudemys scripta elegans in a biphasic mode, characterized half-lives of 5 and 100 min. Acetylation and deacetylatio... |
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Multiple-dose pharmacokinetics of 12 milligrams of trimethoprim and 60 milligrams of sulfamethoxazole per kilogram of body weight per day in healthy volunteers.
Antimicrob. Agents Chemother. 37(3) , 448-52, (1993) The disposition of 12 mg of trimethoprim and 60 mg of sulfamethoxazole per kg of body weight in six healthy male volunteers is described. The daily dose was evenly divided and administered orally ever... |
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Sampling the lipogenic hepatic acetyl-CoA pool in vivo in the rat. Comparison of xenobiotic probe to values predicted from isotopomeric distribution in circulating lipids and measurement of lipogenesis and acetyl-CoA dilution.
J. Biol. Chem. 266(17) , 10912-9, (1991) The acetylation of xenobiotics may provide a means for sampling hepatic cytosolic acetyl-CoA in vivo for isotopic studies of lipogenesis. Here, we test the accuracy of acetylated-sulfamethoxazole (SMX... |
| Sulfamethoxazole impurity A |
| N-Acetyl Sulfamethoxazole |
| N4-Acetylsulfamethoxazole |
| N-[4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl]acetamide |
| N-{4-{[(5-Methyl-3-isoxazolyl)amino]sulfonyl}phenyl}acetamide Sulfisomezole-N4-acetate |
| Sulfamethoxazole EP Impurity A |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: N4-Acetylsulfamethoxazole
- Price: ￥1130.0/25mg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: N4-Acetylsulfamethoxazole
- Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: N-(4-(N-(5-METHYLISOXAZOL-3-YL)SULFAMOYL)PHENYL)ACETAMIDE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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