NBD-14107
Modify Date: 2023-02-25 19:25:45
NBD-14107 structure
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Common Name | NBD-14107 | ||
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| CAS Number | 2086328-94-9 | Molecular Weight | 412.84 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H15ClF2N4O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NBD-14107A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; exhibits antiviral activity against a large panel of HIV-1 Env-pseudotyped viruses representing diverse subtypes of clinical isolates with mean EC50 of 0.49 uM; also inhibits HIV-1 RT with IC50 of 8.4 uM; exhibits improving the potency, toxicity, and ADMET profile compared with NBD-14010. HIV Preclinical |
| Name | NBD-14107 |
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| Description | A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; exhibits antiviral activity against a large panel of HIV-1 Env-pseudotyped viruses representing diverse subtypes of clinical isolates with mean EC50 of 0.49 uM; also inhibits HIV-1 RT with IC50 of 8.4 uM; exhibits improving the potency, toxicity, and ADMET profile compared with NBD-14010. HIV Preclinical |
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| References | References 1. Curreli F, et al. J Med Chem. 2017 Apr 13;60(7):3124-3153. View Related Products by Target HIV HIV |
| Molecular Formula | C17H15ClF2N4O2S |
|---|---|
| Molecular Weight | 412.84 |