PD 166793 structure
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Common Name | PD 166793 | ||
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CAS Number | 199850-67-4 | Molecular Weight | 412.29800 | |
Density | 1.457g/cm3 | Boiling Point | 562.069ºC at 760 mmHg | |
Molecular Formula | C17H18BrNO4S | Melting Point | 192-193℃ | |
MSDS | N/A | Flash Point | 293.729ºC |
Use of PD 166793PD-166793 is a cell-permeable biphenylsulfonylvaline compound that acts as a potent inhibitor against MMP-2, -3, and -13 (IC50 = 47, 12, and 8 nM, respectively) and a weaker inhibitor against AMP deaminase (20% inhibition at 0.1 μM), MMP-1, -7, -9, and -14 (IC50 = 6.1, 7.2, 7.9, and 0.24 μM, respectively). Shown to offer therapeutic benefits in vivo in various animal models of heart failure and diabetes. |
Name | (2S)-2-[[4-(4-bromophenyl)phenyl]sulfonylamino]-3-methylbutanoic acid |
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Density | 1.457g/cm3 |
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Boiling Point | 562.069ºC at 760 mmHg |
Melting Point | 192-193℃ |
Molecular Formula | C17H18BrNO4S |
Molecular Weight | 412.29800 |
Flash Point | 293.729ºC |
Exact Mass | 411.01400 |
PSA | 91.85000 |
LogP | 4.97530 |
Vapour Pressure | 0mmHg at 25°C |
Index of Refraction | 1.597 |
Storage condition | Desiccate at +4°C |
Precursor 3 | |
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DownStream 0 |