Suberic acid-d4

Modify Date: 2024-01-05 16:31:23

Suberic acid-d4 Structure
Suberic acid-d4 structure
Common Name Suberic acid-d4
CAS Number 19031-57-3 Molecular Weight 178.21900
Density N/A Boiling Point N/A
Molecular Formula C8H10D4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Suberic acid-d4


Suberic acid-d4 is the deuterium labeled Suberic acid[1]. Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency[2].

 Names

Name 1,8-octanedioic-2,2,7,7-d4 acid
Synonym More Synonyms

 Suberic acid-d4 Biological Activity

Description Suberic acid-d4 is the deuterium labeled Suberic acid[1]. Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Gregersen N, et al. General (medium-chain) acyl-CoA dehydrogenase deficiency (non-ketotic dicarboxylic aciduria): quantitative urinary excretion pattern of 23 biologically significant organic acids in three cases. Clin Chim Acta. 1983 Aug 15;132(2):181-91.  

 Chemical & Physical Properties

Molecular Formula C8H10D4O4
Molecular Weight 178.21900
Exact Mass 178.11400
PSA 74.60000
LogP 1.49620

 Synonyms

2,2,7,7-tetradeuterio-octanedioic acid
1,2-dichloroisopropylbenzene
<2,7-2H4>-Octandisaeure
1,2-dichloro-2-phenylpropane
1,2-Dichlor-2-phenylpropan