Pinostrobin chalcone

Modify Date: 2024-01-12 09:30:41

Pinostrobin chalcone Structure
Pinostrobin chalcone structure
Common Name Pinostrobin chalcone
CAS Number 18956-15-5 Molecular Weight 270.28
Density 1.3±0.1 g/cm3 Boiling Point 521.1±50.0 °C at 760 mmHg
Molecular Formula C16H14O4 Melting Point 145ºC
MSDS N/A Flash Point 198.0±23.6 °C

 Use of Pinostrobin chalcone


Pinostrobin chalcone is found to be potent natural cytotoxic compounds against MDA-MB-231 and HT-29 colon cancer cell lines(IC50 = 20.42±2.23 and 22.51±0.42 μg/mL)[1].

 Names

Name 2',6'-dihydroxy-4'-methoxychalcone
Synonym More Synonyms

 Pinostrobin chalcone Biological Activity

Description Pinostrobin chalcone is found to be potent natural cytotoxic compounds against MDA-MB-231 and HT-29 colon cancer cell lines(IC50 = 20.42±2.23 and 22.51±0.42 μg/mL)[1].
Related Catalog
References

[1]. Mohammed I ,et al. Isolation of cardamonin, pinostrobin chalcone from the rhizomes of Boesenbergia rotunda (L.) Mansf. and their cytotoxic effects on H-29 and MDA-MB-231 cancer cell lines[J]. The Natural Products Journal, 2019, 9(4):341-348.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 521.1±50.0 °C at 760 mmHg
Melting Point 145ºC
Molecular Formula C16H14O4
Molecular Weight 270.28
Flash Point 198.0±23.6 °C
Exact Mass 270.089203
PSA 66.76000
LogP 4.40
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.658

 Safety Information

Hazard Codes Xi
HS Code 2914509090

 Synthetic Route

~45%

Pinostrobin chalcone Structure

Pinostrobin chalcone

CAS#:18956-15-5

Literature: Liu, Tao; Hu, Yongzhou Synthetic Communications, 2004 , vol. 34, # 17 p. 3209 - 3218

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Pinostrobin chalcone Structure

Pinostrobin chalcone

CAS#:18956-15-5

Literature: Pouget, Christelle; Lauthier, Fabienne; Simon, Alain; Fagnere, Catherine; Basly, Jean-Philippe; Delage, Christiane; Chulia, Albert-Jose Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 24 p. 3095 - 3097

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

2,6-dihydroxyl-4-methoxyl-chalcone
2',6'-Dihydroxy-4'-methoxy-trans-chalkon
DIHYDROXY-4'-METHOXYCHALCONE,2',6'
(2E)-1-(2,6-Dihydroxy-4-methoxyphenyl)-3-phenyl-2-propen-1-one
2-Propen-1-one, 1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenyl-, (2E)-
2-Propen-1-one, 1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenyl-, (E)-
Pistrobin chalcone
Pinostrobin chalcone
2',6'-dihydroxy-4'-methoxy-trans-chalcone
Chalcone, 2',6'-dihydroxy-4'-methoxy-
plnostrobin chalcone
(2E)-1-(2,6-Dihydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one
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