Bis-sulfone-PEG4-DBCO

Modify Date: 2024-01-07 00:36:13

Bis-sulfone-PEG4-DBCO Structure
Bis-sulfone-PEG4-DBCO structure
Common Name Bis-sulfone-PEG4-DBCO
CAS Number 1854034-70-0 Molecular Weight 1006.19
Density N/A Boiling Point N/A
Molecular Formula C54H59N3O12S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-sulfone-PEG4-DBCO


Bis-sulfone-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis-sulfone-PEG4-DBCO

 Bis-sulfone-PEG4-DBCO Biological Activity

Description Bis-sulfone-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.

 Chemical & Physical Properties

Molecular Formula C54H59N3O12S2
Molecular Weight 1006.19
Storage condition -20°C