Anisodamine

Modify Date: 2024-01-02 19:21:24

Anisodamine Structure
Anisodamine structure
Common Name Anisodamine
CAS Number 17659-49-3 Molecular Weight 305.369
Density 1.3±0.1 g/cm3 Boiling Point 474.6±45.0 °C at 760 mmHg
Molecular Formula C17H23NO4 Melting Point N/A
MSDS N/A Flash Point 240.8±28.7 °C

 Use of Anisodamine


Racanisodamine is one of the racemic isomers of anisodamine, resembles anisodamine in pharmacological effect. Racanisodamine is a non-selective muscarinic antagonist, used as a component of eye drops for myopic control[1].

 Names

Name [(3S,5S,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate
Synonym More Synonyms

 Anisodamine Biological Activity

Description Racanisodamine is one of the racemic isomers of anisodamine, resembles anisodamine in pharmacological effect. Racanisodamine is a non-selective muscarinic antagonist, used as a component of eye drops for myopic control[1].
Related Catalog
References

[1]. Chen Z, et al. Effects of 0.05% racanisodamine on pupil size and accommodation. Optom Vis Sci. 2010 Dec;87(12):966-70.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 474.6±45.0 °C at 760 mmHg
Molecular Formula C17H23NO4
Molecular Weight 305.369
Flash Point 240.8±28.7 °C
Exact Mass 305.162720
PSA 70.00000
LogP 0.25
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.600

 Safety Information

Hazard Codes Xi

 Synthetic Route

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Anisodamine Structure

Anisodamine

CAS#:17659-49-3

Literature: Phytochemistry (Elsevier), , vol. 28, # 12 p. 3507 - 3510

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Anisodamine Structure

Anisodamine

CAS#:17659-49-3

Literature: Planta Medica, , vol. 71, # 3 p. 249 - 253

 Synonyms

(1S)-6-Hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate
6-Hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate
benzeneacetic acid, α-(hydroxymethyl)-, (1R)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
Benzeneacetic acid, α-(hydroxymethyl)-, 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
3-Hydroxy-2-phenyl-propionic acid 6-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester
α-(hydroxymethyl)benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester
6-hydroxyhyoscyamine
Anisodamine
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