Lacosamide

Modify Date: 2024-01-04 19:15:34

Lacosamide structure	Common Name	Lacosamide
	CAS Number	175481-36-4	Molecular Weight	250.294
	Density	1.1±0.1 g/cm3	Boiling Point	536.4±50.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₁₈N₂O₃	Melting Point	141-143?C
	MSDS	N/A	Flash Point	278.2±30.1 °C
	Symbol	GHS02, GHS07	Signal Word	Danger

Use of Lacosamide

Lacosamide (Vimpat; Erlosamide) is a medication developed for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain.

Name	(2R)-2-acetamido-N-benzyl-3-methoxypropanamide
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	536.4±50.0 °C at 760 mmHg
Melting Point	141-143?C
Molecular Formula	C₁₃H₁₈N₂O₃
Molecular Weight	250.294
Flash Point	278.2±30.1 °C
Exact Mass	250.131744
PSA	67.43000
LogP	0.90
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.520

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H225-H302 + H312 + H332-H319
Precautionary Statements	P210-P280-P305 + P351 + P338
Hazard Codes	F,Xn
Risk Phrases	11-20/21/22-36
Safety Phrases	16-26-36/37
RIDADR	UN 1648 3 / PGII
WGK Germany	2.0

Molecule of the month. Lacosamide.

Drug News Perspect. 17(10) , 689, (2004)

SPM-927 (Schwarz Pharma).

IDrugs 6(5) , 479-85, (2003)

Schwarz Pharma, under license from Harris FRC, is developing SPM-927, synthesized by researchers at the University of Houston, for the potential treatment of epilepsy and neuropathic pain.

Does SPM 927 have an analgesic effect in human neuropathic pain? An open label study.

Neurosci. Lett. 352(2) , 117-20, (2003)

The aim of the study is to establish if the putative anticonvulsant SPM 927 has an analgesic effect in human neuropathic pain and to assess its tolerability. This is an open label study of 25 adult hu...

Vimpat

Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)-

Harkoseride

Erlosamide

Lacosamide

UNII-563KS2PQY5

SPM 927

N-Acetyl-N-benzyl-O-methyl-D-serinamide

S1253_Selleck