Acetone thiosemicarbazone

Modify Date: 2024-01-02 12:14:54

Acetone thiosemicarbazone Structure
Acetone thiosemicarbazone structure
Common Name Acetone thiosemicarbazone
CAS Number 1752-30-3 Molecular Weight 131.199
Density 1.2±0.1 g/cm3 Boiling Point 213.8±23.0 °C at 760 mmHg
Molecular Formula C4H9N3S Melting Point 174-175°C
MSDS N/A Flash Point 83.1±22.6 °C

 Names

Name Acetone Thiosemicarbazone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 213.8±23.0 °C at 760 mmHg
Melting Point 174-175°C
Molecular Formula C4H9N3S
Molecular Weight 131.199
Flash Point 83.1±22.6 °C
Exact Mass 131.051712
PSA 82.50000
LogP -0.44
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.569

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AL7350000
CHEMICAL NAME :
Acetone, thiosemicarbazone
CAS REGISTRY NUMBER :
1752-30-3
LAST UPDATED :
199712
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C4-H9-N3-S
MOLECULAR WEIGHT :
131.22
WISWESSER LINE NOTATION :
SUYZMNUY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
48500 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0539438
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
72 mg/kg/4H
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0539426
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
23 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 122,110,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
19700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0539438
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0539438
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Ocular
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - acute pulmonary edema Blood - hemorrhage
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0539438

 Safety Information

Risk Phrases R21;R25;R26
Safety Phrases S22-S28-S36/37/39
RIDADR 2811
RTECS AL7350000
HS Code 2930909090

 Synthetic Route

~%

Acetone thiosemicarbazone Structure

Acetone thiosem...

CAS#:1752-30-3

Literature: Yakugaku Zasshi, , vol. 73, p. 460,462 Chem.Abstr., , p. 5145

~%

Acetone thiosemicarbazone Structure

Acetone thiosem...

CAS#:1752-30-3

Literature: Svensk Kemisk Tidskrift, , vol. 67, p. 361,363

~96%

Acetone thiosemicarbazone Structure

Acetone thiosem...

CAS#:1752-30-3

Literature: Lhuachan, Sanchai; Siripaisarnpipat, Sutatip; Chaichit, Narongsak European Journal of Inorganic Chemistry, 2003 , # 2 p. 263 - 267

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

(propan-2-ylideneamino)thiourea
Acetone thiosemicarbazone
MFCD00022153
EINECS 217-137-9