Sutezolid
Modify Date: 2024-01-11 09:09:54
Sutezolid structure
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Common Name | Sutezolid | ||
|---|---|---|---|---|
| CAS Number | 168828-58-8 | Molecular Weight | 353.41200 | |
| Density | 1.321g/cm3 | Boiling Point | 609ºC at 760 mmHg | |
| Molecular Formula | C16H20FN3O3S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 322.1ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of SutezolidSutezolid (PNU-100480) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis.Target: AntibacterialSutezolid is a much-awaited drug candidate for treatment of Mycobacterium tuberculosis. [1] Sutezolid is an oxazolidinone antibiotic currently in development as a treatment forextensively drug-resistant tuberculosis. Sutezolid is a linezolid analog with superior bactericidal activity against Mycobacterium tuberculosis in the hollow fiber, whole blood and mouse models. Like linezolid, it is unaffected by mutations conferring resistance to standard TB drugs. This study of sutezolid is its first in tuberculosis patients.[2] |
| Name | N-[[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide |
|---|---|
| Synonym | More Synonyms |
| Description | Sutezolid (PNU-100480) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis.Target: AntibacterialSutezolid is a much-awaited drug candidate for treatment of Mycobacterium tuberculosis. [1] Sutezolid is an oxazolidinone antibiotic currently in development as a treatment forextensively drug-resistant tuberculosis. Sutezolid is a linezolid analog with superior bactericidal activity against Mycobacterium tuberculosis in the hollow fiber, whole blood and mouse models. Like linezolid, it is unaffected by mutations conferring resistance to standard TB drugs. This study of sutezolid is its first in tuberculosis patients.[2] |
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| Related Catalog | |
| References |
| Density | 1.321g/cm3 |
|---|---|
| Boiling Point | 609ºC at 760 mmHg |
| Molecular Formula | C16H20FN3O3S |
| Molecular Weight | 353.41200 |
| Flash Point | 322.1ºC |
| Exact Mass | 353.12100 |
| PSA | 87.18000 |
| LogP | 2.36110 |
| Vapour Pressure | 8.97E-15mmHg at 25°C |
| Index of Refraction | 1.584 |
| Storage condition | 2-8℃ |
![(R)-[3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl azide structure](https://www.chemsrc.com/caspic/198/168828-74-8.png)
| (S)-N-[[3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide |
| N[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide |
| Sutezolid [USAN] |
| N-{[3-(3-Fluoro-4-(1,4-thiazaperhydroin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide |
| Sutezolid |
| Sutezolid [INN] |