(S)-3,5-DHPG structure
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Common Name | (S)-3,5-DHPG | ||
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CAS Number | 162870-29-3 | Molecular Weight | 183.161 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | 448.8±33.0 °C at 760 mmHg | |
Molecular Formula | C8H9NO4 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 225.2±25.4 °C |
Use of (S)-3,5-DHPG(S)-3,5-DHPG is a weak, but selective group I metabotropic glutamate receptors (mGluRs) agonist with Ki values of 0.9 µM and 3.9 µM for mGluR1a and mGluR5a, respectively[1]. (S)-3,5-DHPG exhibits anxiolytic activity in rats subjected to hypoxia[2]. |
Name | (S)-3,5-Dihydroxyphenylglycine hydrate |
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Synonym | More Synonyms |
Description | (S)-3,5-DHPG is a weak, but selective group I metabotropic glutamate receptors (mGluRs) agonist with Ki values of 0.9 µM and 3.9 µM for mGluR1a and mGluR5a, respectively[1]. (S)-3,5-DHPG exhibits anxiolytic activity in rats subjected to hypoxia[2]. |
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Related Catalog | |
Target |
mGluR1a:0.9 μM (Ki) mGluR5a:3.9 μM (Ki) |
In Vitro | (S)-3,5-DHPG specifically displaces high-affinity quisqualate sites, the putative group I mGlu binding sites[1]. |
In Vivo | (S)-3,5-DHPG (icv; 0.01, 0.1 and 1.0 nmol/5 μL) improves consolidation and retrieval and exhibits anxiolytic activity in dose-dependent manner in male Wistar rats weighing 160-180 g subjected to hypoxia[2]. |
References |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 448.8±33.0 °C at 760 mmHg |
Molecular Formula | C8H9NO4 |
Molecular Weight | 183.161 |
Flash Point | 225.2±25.4 °C |
Exact Mass | 183.053162 |
PSA | 103.78000 |
LogP | -0.52 |
Vapour Pressure | 0.0±1.1 mmHg at 25°C |
Index of Refraction | 1.680 |
Hazard Codes | Xi: Irritant; |
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Risk Phrases | R36/37/38 |
Safety Phrases | S26 |
HS Code | 2922509090 |
HS Code | 2922509090 |
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Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Benzeneacetic acid, α-amino-3,5-dihydroxy-, (αS)- |
(2S)-Amino(3,5-dihydroxyphenyl)acetic acid |
Amino(3,5-dihydroxyphenyl)acetic acid |
Benzeneacetic acid, α-amino-3,5-dihydroxy- |
(2S)-amino(3,5-dihydroxyphenyl)ethanoic acid |
UNII:5YR2N37E6D |
(S)-3,5-DHPG,(S)-3,5-Dihydroxyphenylglycine |