1,3-Propanediol,1,3-dimethanesulfonate

DATA ITEMS CITED :

13

MOLECULAR FORMULA :

C5-H12-O6-S2

MOLECULAR WEIGHT :

232.29

WISWESSER LINE NOTATION :

WS1&O3OSW1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

500 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

50 mg/kg

SEX/DURATION :

female 15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - urogenital system Reproductive - Effects on Newborn - delayed effects

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

50 mg/kg

SEX/DURATION :

female 15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Newborn - germ cell effects (in offspring) Reproductive - Effects on Newborn - delayed effects

TYPE OF TEST :

Sex chromosome loss and nondisjunction

TYPE OF TEST :

Cytogenetic analysis

TYPE OF TEST :

Dominant lethal test

TYPE OF TEST :

Dominant lethal test

TYPE OF TEST :

Dominant lethal test

TYPE OF TEST :

Dominant lethal test

TYPE OF TEST :

Dominant lethal test

MUTATION DATA

TYPE OF TEST :

DNA damage

TEST SYSTEM :

Rodent - rat Cells - not otherwise specified

DOSE/DURATION :

250 umol/L

REFERENCE :

BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 32,2297,1983