Indole-2-carboxylic acid

Modify Date: 2024-01-01 21:49:15

Indole-2-carboxylic acid Structure
Indole-2-carboxylic acid structure
Common Name Indole-2-carboxylic acid
CAS Number 1477-50-5 Molecular Weight 161.157
Density 1.4±0.1 g/cm3 Boiling Point 419.6±18.0 °C at 760 mmHg
Molecular Formula C9H7NO2 Melting Point 202-206 °C(lit.)
MSDS USA Flash Point 207.6±21.2 °C

 Use of Indole-2-carboxylic acid


Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].

 Names

Name Indole-2-carboxylic acid
Synonym More Synonyms

 Indole-2-carboxylic acid Biological Activity

Description Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. 2-Indolecarboxylic acid.

[2]. J E Huettner, et al. Indole-2-carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor. Science. 1989 Mar 24;243(4898):1611-3.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 419.6±18.0 °C at 760 mmHg
Melting Point 202-206 °C(lit.)
Molecular Formula C9H7NO2
Molecular Weight 161.157
Flash Point 207.6±21.2 °C
Exact Mass 161.047684
PSA 53.09000
LogP 2.31
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.726

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;Xn: Harmful;
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS NK7882812
HS Code 29339990

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

1H-Indole-2-carboxylic acid
T56 BMJ CVQ
Indole-2-carboxylic acid
2-Carboxyindole
2-Indolecarboxylic acid
MFCD00005611
EINECS 216-030-4
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