Indole-2-carboxylic acid structure
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Common Name | Indole-2-carboxylic acid | ||
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CAS Number | 1477-50-5 | Molecular Weight | 161.157 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 419.6±18.0 °C at 760 mmHg | |
Molecular Formula | C9H7NO2 | Melting Point | 202-206 °C(lit.) | |
MSDS | USA | Flash Point | 207.6±21.2 °C |
Use of Indole-2-carboxylic acidIndole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2]. |
Name | Indole-2-carboxylic acid |
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Synonym | More Synonyms |
Description | Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2]. |
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Related Catalog | |
Target |
Human Endogenous Metabolite |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 419.6±18.0 °C at 760 mmHg |
Melting Point | 202-206 °C(lit.) |
Molecular Formula | C9H7NO2 |
Molecular Weight | 161.157 |
Flash Point | 207.6±21.2 °C |
Exact Mass | 161.047684 |
PSA | 53.09000 |
LogP | 2.31 |
Vapour Pressure | 0.0±1.0 mmHg at 25°C |
Index of Refraction | 1.726 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi: Irritant;Xn: Harmful; |
Risk Phrases | R36/37/38 |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | NK7882812 |
HS Code | 29339990 |
Precursor 10 | |
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DownStream 10 | |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.
Bioorg. Med. Chem. 17 , 5219-28, (2009) In the light of known HDAC inhibitors, 33 carboxylic acid derivatives were tested to understand the structural requirements for HDAC inhibition activity. Several modifications were applied to develop ... |
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In vitro and in vivo assessment of the antioxidant activity of melatonin and related indole derivatives.
Gen. Physiol. Biophys. 21(2) , 153-62, (2002) Effects of melatonin and some structurally related indole compounds were studied by in vitro methods such as (i) an inhibition of the hyaluronic acid degradation and (ii) a standard lipid peroxidation... |
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Protonated carbonic acid and reactive intermediates in the acidic decarboxylation of indolecarboxylic acids.
J. Org. Chem. 77(15) , 6505-9, (2012) Elucidation of the mechanism for decarboxylation of indolecarboxylic acids over a wide range of solution acidity reveals the importance of protonated carbonic acid (PCA) as a reaction intermediate. In... |
1H-Indole-2-carboxylic acid |
T56 BMJ CVQ |
Indole-2-carboxylic acid |
2-Carboxyindole |
2-Indolecarboxylic acid |
MFCD00005611 |
EINECS 216-030-4 |