CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UT5009000
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CHEMICAL NAME :
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3-Pyridinemethanol, 5-hydroxy-4-(methoxymethyl)-6-methyl-
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CAS REGISTRY NUMBER :
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1464-33-1
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BEILSTEIN REFERENCE NO. :
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0150788
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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7
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MOLECULAR FORMULA :
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C9-H13-N-O3
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MOLECULAR WEIGHT :
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183.23
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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540 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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PSDTAP Proceedings of the European Society for the Study of Drug Toxicity. (Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see PESTD5. Volume(issue)/page/year: 4,179,1964
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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32 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold
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REFERENCE :
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PSDTAP Proceedings of the European Society for the Study of Drug Toxicity. (Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see PESTD5. Volume(issue)/page/year: 4,179,1964
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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23 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold
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REFERENCE :
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PSDTAP Proceedings of the European Society for the Study of Drug Toxicity. (Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see PESTD5. Volume(issue)/page/year: 4,179,1964
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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20 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold
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REFERENCE :
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PSDTAP Proceedings of the European Society for the Study of Drug Toxicity. (Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see PESTD5. Volume(issue)/page/year: 4,179,1964
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Mammal - dog
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DOSE/DURATION :
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8 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression
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REFERENCE :
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PSDTAP Proceedings of the European Society for the Study of Drug Toxicity. (Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see PESTD5. Volume(issue)/page/year: 4,179,1964
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Mammal - cat
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DOSE/DURATION :
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9 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression
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REFERENCE :
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PSDTAP Proceedings of the European Society for the Study of Drug Toxicity. (Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see PESTD5. Volume(issue)/page/year: 4,179,1964
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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17 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression
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REFERENCE :
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PSDTAP Proceedings of the European Society for the Study of Drug Toxicity. (Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see PESTD5. Volume(issue)/page/year: 4,179,1964
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