Sodium deoxycholate monohydrate structure
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Common Name | Sodium deoxycholate monohydrate | ||
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CAS Number | 145224-92-6 | Molecular Weight | 432.56900 | |
Density | N/A | Boiling Point | 581.5ºC at 760mmHg | |
Molecular Formula | C24H41NaO5 | Melting Point | >300ºC | |
MSDS | Chinese USA | Flash Point | 319.5ºC | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Sodium deoxycholate monohydrateDeoxycholic acid (cholanoic acid) sodium hydrate,a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5[1][2]. |
Name | Sodium Deoxycholate Monohydrate |
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Synonym | More Synonyms |
Description | Deoxycholic acid (cholanoic acid) sodium hydrate,a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5[1][2]. |
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Related Catalog | |
Target |
Microbial Metabolite |
In Vitro | Deoxycholic acid sodium hydrate (DCA) (100 μM) induces the production of gastric cancer cell line MGC803 resistant to acidified bile acids and enhances their survival and proliferation activity under bile acid stress[2]. Deoxycholic acid sodium hydrate (DCA) (100 μM)-induced resistant cells shows altered morphology, significantly elevated telomerase activity, better cell viability and reduces apoptosis compared to normal MGC803 cells[2]. |
References |
Boiling Point | 581.5ºC at 760mmHg |
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Melting Point | >300ºC |
Molecular Formula | C24H41NaO5 |
Molecular Weight | 432.56900 |
Flash Point | 319.5ºC |
Exact Mass | 432.28500 |
PSA | 89.82000 |
LogP | 3.07890 |
Dissolution of gall-stones in vitro.
J. Indian Med. Assoc. 89 , 129, (1991) An in vitro study on dissolution of 36 gall-stones obtained from 3 patients (12 stones from each patient) was carried out in heparin, bile salt and clofibrate solutions of different strengths. Heparin... |
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Immobilization of lipoxygenase in an alginate-silicate solgel matrix: formation of fatty acid hydroperoxides Hsu, A., et al.
Biotechnol. Lett. 19 , 71, (1997)
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Liquid crystals and phase equilibria binary bile salt-water systems. Marques EF, et al.
Langmuir 16(11) , 5178-5186, (2000)
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MFCD00150750 |
EINECS 206-132-7 |
Sodium deoxycholate monohydrate |
sodium,(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate,hydrate |
DEOXYCHOLIC ACID SODIUM SALT MONOHYDRATE |