5'-Bromo-2'-hydroxyacetophenone

Modify Date: 2024-01-02 00:18:47

5'-Bromo-2'-hydroxyacetophenone Structure
5'-Bromo-2'-hydroxyacetophenone structure
Common Name 5'-Bromo-2'-hydroxyacetophenone
CAS Number 1450-75-5 Molecular Weight 215.044
Density 1.6±0.1 g/cm3 Boiling Point 282.6±25.0 °C at 760 mmHg
Molecular Formula C8H7BrO2 Melting Point 58-61ºC
MSDS Chinese USA Flash Point 124.7±23.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 5'-Bromo-2'-hydroxyacetophenone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 282.6±25.0 °C at 760 mmHg
Melting Point 58-61ºC
Molecular Formula C8H7BrO2
Molecular Weight 215.044
Flash Point 124.7±23.2 °C
Exact Mass 213.962936
PSA 37.30000
LogP 3.11
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.592
Water Solubility Soluble in Chloroform

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KM5556350
CHEMICAL NAME :
Ethanone, 1-(5-bromo-2-hydroxyphenyl)-
CAS REGISTRY NUMBER :
1450-75-5
BEILSTEIN REFERENCE NO. :
2045140
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H7-Br-O2
MOLECULAR WEIGHT :
215.06

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976- Volume(issue)/page/year: 20,480,1981

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS KM5556350
HS Code 2914700090

 Synthetic Route

 Customs

HS Code 2914700090
Summary HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

 Articles5

More Articles
N'-[1-(5-Bromo-2-hydroxy-phen-yl)ethyl-idene]-3,4,5-trihydroxy-benzohydrazide dimethyl sulfoxide solvate trihydrate.

Acta Crystallogr. Sect. E Struct. Rep. Online 66(Pt 3) , o721, (2010)

The benzohydrazide mol-ecule in the title compound, C(15)H(13)BrN(2)O(5)·C(2)H(6)OS·3H(2)O, is almost planar with an r.m.s. deviation for the non-H atoms of 0.078 Å. The organic mol-ecules, water and ...

Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries.

Bioorg. Med. Chem. Lett. 14(24) , 6083-7, (2004)

A solution-phase multiple-parallel synthesis approach was employed for the preparation of 6-, 7- and 8-aryl-substituted chromenone libraries, which were screened as inhibitors of the DNA repair enzyme...

Spermicidal activity of oxovanadium(IV) complexes of 1, 10-phenanthroline, 2,2'-bipyridyl, 5'-bromo-2'-hydroxyacetophenone and derivatives in humans.

Biol. Reprod. 60(2) , 435-44, (1999)

We have recently reported that tetrahedral metallocene complexes containing vanadium(IV) (vanadocene) have potent spermicidal activity against human sperm. The spermicidal activity was dependent on va...

 Synonyms

Ethanone, 1-(5-bromo-2-hydroxyphenyl)-
1-(5-Bromo-2-hydroxyphenyl)ethanone
2-Acetyl-4-bromophenol
MFCD00191850