5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine

Modify Date: 2023-01-11 10:09:28

5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine structure	Common Name	5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine
	CAS Number	144881-48-1	Molecular Weight	304.38700
	Density	1.26g/cm3	Boiling Point	462.7ºC at 760mmHg
	Molecular Formula	C₁₆H₂₄N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	233.6ºC

Name	5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine

Density	1.26g/cm3
Boiling Point	462.7ºC at 760mmHg
Molecular Formula	C₁₆H₂₄N₄O₂
Molecular Weight	304.38700
Flash Point	233.6ºC
Exact Mass	304.19000
PSA	60.82000
LogP	1.56190
Vapour Pressure	9.68E-09mmHg at 25°C
Index of Refraction	1.618

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RP6746500

CHEMICAL NAME :: 2-Oxazolamine, 4,5-dihydro-5-((4-(4-methoxyphenyl)-3-methyl-1-pipera zinyl)methyl)-

CAS REGISTRY NUMBER :: 144881-48-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C16-H24-N4-O2

MOLECULAR WEIGHT :: 304.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 524 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 27,437,1992

1-(4-METHOXYPHENYL)-2-METHYLPIPERAZINE, 1:1 MIXTURE OF CONFORMERS structure

1-(4-METHOXYPHE...

CAS#:35947-12-7

~%

5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine Structure

5-[[4-(2-ethoxy...

CAS#:144881-48-1

Literature: Bosc; Jarry; Carpy; Panconi; Descas European Journal of Medicinal Chemistry, 1992 , vol. 27, # 5 p. 437 - 442

1-chloro-3-(4-(4-methoxyphenyl)-3-methylpiperazin-1-yl)propan-2-ol structure

1-chloro-3-(4-(...

CAS#:1026400-08-7

~%

5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine Structure

5-[[4-(2-ethoxy...

CAS#:144881-48-1

Literature: Bosc; Jarry; Carpy; Panconi; Descas European Journal of Medicinal Chemistry, 1992 , vol. 27, # 5 p. 437 - 442

cyanamide,sodium structure

cyanamide,sodium

CAS#:19981-17-0

1-chloro-3-(4-(4-methoxyphenyl)-3-methylpiperazin-1-yl)propan-2-ol structure

1-chloro-3-(4-(...

CAS#:1026400-08-7

~9%

5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine Structure

5-[[4-(2-ethoxy...

CAS#:144881-48-1

Literature: Bosc; Jarry; Carpy; Panconi; Descas European Journal of Medicinal Chemistry, 1992 , vol. 27, # 5 p. 437 - 442

Precursor 2
CAS#:35947-12-7 1-(4-METHOXYPHE... CAS#:19981-17-0 cyanamide,sodium
DownStream 0

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3