Spermine NONOate

Modify Date: 2024-01-02 15:04:30

Spermine NONOate Structure
Spermine NONOate structure
Common Name Spermine NONOate
CAS Number 136587-13-8 Molecular Weight 262.352
Density 1.2±0.1 g/cm3 Boiling Point 425.4±55.0 °C at 760 mmHg
Molecular Formula C10H26N6O2 Melting Point 105-107ºC
MSDS USA Flash Point 211.1±31.5 °C

 Use of Spermine NONOate


Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing[1].

 Names

Name Spermine Bis (Nitric Oxide) Adduct
Synonym More Synonyms

 Spermine NONOate Biological Activity

Description Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing[1].
Related Catalog
In Vitro Spermine NONOate has a half-life of 39 minutes and 230 minutes at 37°C and 22-25°C, respectively[1].
References

[1]. A Ramamurthi , et al. Measurement and modeling of nitric oxide release rates for nitric oxide donors. Chem Res Toxicol. 1997 Apr;10(4):408-13.

[2]. K Homer, et al. In vitro comparison of two NONOates (novel nitric oxide donors) on rat pulmonary arteries. Eur J Pharmacol. 1998 Aug 28;356(1):49-57.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 425.4±55.0 °C at 760 mmHg
Melting Point 105-107ºC
Molecular Formula C10H26N6O2
Molecular Weight 262.352
Flash Point 211.1±31.5 °C
Exact Mass 262.211731
PSA 120.21000
LogP -1.03
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.554

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22;S24/25
RIDADR NONH for all modes of transport
HS Code 2928000090

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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 Synonyms

N-[3-aminopropyl-[4-(3-aminopropylamino)butyl]amino]-N-hydroxynitrous amide
1-(3-Aminopropyl)-1-{4-[(3-aminopropyl)amino]butyl}-2-hydroxy-3-oxotriazane
1,3-Propanediamine, N-[4-[1-(3-aminopropyl)-2-hydroxy-3-oxotriazanyl]butyl]-
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Price: ¥1500/10 mg

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