Dolutegravir intermediate-1
Modify Date: 2024-01-03 02:15:20
Dolutegravir intermediate-1 structure
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Common Name | Dolutegravir intermediate-1 | ||
|---|---|---|---|---|
| CAS Number | 1335210-23-5 | Molecular Weight | 315.276 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 474.1±45.0 °C at 760 mmHg | |
| Molecular Formula | C13H17NO8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 240.5±28.7 °C | |
Use of Dolutegravir intermediate-1Dolutegravir intermediate-1 is a novel synthetic intermediate of dolutegravir extracted from patent WO 2016125192 A2. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-l infection. |
| Name | 2,5-Pyridinedicarboxylic acid, 1-(2,2-dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-, 2-methyl ester |
|---|---|
| Synonym | More Synonyms |
| Description | Dolutegravir intermediate-1 is a novel synthetic intermediate of dolutegravir extracted from patent WO 2016125192 A2. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-l infection. |
|---|---|
| Related Catalog | |
| References |
[1]. Sivaram Prasad, et al. Process for the preparation of dolutegravir . WO 2016125192 A2. |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 474.1±45.0 °C at 760 mmHg |
| Molecular Formula | C13H17NO8 |
| Molecular Weight | 315.276 |
| Flash Point | 240.5±28.7 °C |
| Exact Mass | 315.095428 |
| PSA | 113.29000 |
| LogP | -1.00 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.536 |
| Storage condition | 2-8℃ |
| 1-(2,2-Dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydro-3-pyridinecarboxylic acid |
| 2,5-Pyridinedicarboxylic acid, 1-(2,2-dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-, 2-methyl ester |
| 1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid |
| Dolutegravir intermediate-1 |
| 1-(2,2-Dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-2,5-pyridinedicarboxylic acid 2-methyl ester |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Dolutegravir intermediate-1
- Price: ￥156.0/250mg ￥1906.0/10g ￥106.0/100mg ￥396.0/1g
- Purity: 97.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 1-(2,2-diMethoxyethyl)-5-Methoxy-6-(Methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: 1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: 1-(2,2-diMethoxyethyl)-5-Methoxy-6-(Methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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Price: $83/10mM*1mLinDMSO
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