Silibinin-d5

Modify Date: 2024-01-11 23:40:24

Silibinin-d5 Structure
Silibinin-d5 structure
Common Name Silibinin-d5
CAS Number 1329802-47-2 Molecular Weight 487.47
Density N/A Boiling Point N/A
Molecular Formula C25H17D5O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Silibinin-d5


Silibinin-d5 is the deuterium labeled Silibinin. Silibinin (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration.

 Names

Name Silibinin-d5

 Silibinin-d5 Biological Activity

Description Silibinin-d5 is the deuterium labeled Silibinin. Silibinin (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Woo SM, et al. Silibinin induces apoptosis of HT29 colon carcinoma cells through early growth response-1 (EGR-1)-mediated non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) up-regulation. Chem Biol Interact. 2014 Jan 16;211C:36-43.;Kim TH, et a

 Chemical & Physical Properties

Molecular Formula C25H17D5O10
Molecular Weight 487.47