torilin
Modify Date: 2024-01-11 19:10:10
torilin structure
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Common Name | torilin | ||
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| CAS Number | 13018-10-5 | Molecular Weight | 376.49 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 469.2±45.0 °C at 760 mmHg | |
| Molecular Formula | C22H32O5 | Melting Point | 78-79℃ (methanol ) | |
| MSDS | N/A | Flash Point | 201.0±28.8 °C | |
Use of torilinTorilin is a sesquiterpene with antimicrobial, anticancer, and anti-inflammatory properties. Torilin inhibits LPS-induced NO release, as well as inhibiting iNOS, PGE2, COX-2, NF-α, IL-1β, IL-6, and GM-CSF. Torilin suppresses NF-kB and AP-1 translocation, inhibits TAK1 kinase activation. Subsequently results suppression of MAPK-mediated JNK, p38, ERK1/2, and AP-1 (ATF-2 and c-jun) activation and IKK-mediated I-κBα degradation, p65/p50 activation, and translocation[1]. |
| Name | [(5S,6R,8S,8aR)-5-(2-acetyloxypropan-2-yl)-3,8-dimethyl-2-oxo-4,5,6,7,8,8a-hexahydro-1H-azulen-6-yl] (Z)-2-methylbut-2-enoate |
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| Synonym | More Synonyms |
| Description | Torilin is a sesquiterpene with antimicrobial, anticancer, and anti-inflammatory properties. Torilin inhibits LPS-induced NO release, as well as inhibiting iNOS, PGE2, COX-2, NF-α, IL-1β, IL-6, and GM-CSF. Torilin suppresses NF-kB and AP-1 translocation, inhibits TAK1 kinase activation. Subsequently results suppression of MAPK-mediated JNK, p38, ERK1/2, and AP-1 (ATF-2 and c-jun) activation and IKK-mediated I-κBα degradation, p65/p50 activation, and translocation[1]. |
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| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 469.2±45.0 °C at 760 mmHg |
| Melting Point | 78-79℃ (methanol ) |
| Molecular Formula | C22H32O5 |
| Molecular Weight | 376.49 |
| Flash Point | 201.0±28.8 °C |
| Exact Mass | 376.224976 |
| PSA | 69.67000 |
| LogP | 4.23 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.508 |
| Hazard Codes | Xi |
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| 2-Butenoic acid, 2-methyl-, (3aR,4S,6R,7S)-7-[1-(acetyloxy)-1-methylethyl]-2,3,3a,4,5,6,7,8-octahydro-1,4-dimethyl-2-oxo-6-azulenyl ester, (2Z)- |
| 8-angeloyl-11-acetyl-8,11-dihydroxy-4-guaien-3-one |
| (5S,6R,8S,8aR)-5-(2-Acetoxy-2-propanyl)-3,8-dimethyl-2-oxo-1,2,4,5,6,7,8,8a-octahydro-6-azulenyl (2Z)-2-methyl-2-butenoate |
| torilin |
| 11-acetoxy-8-angeloyl-4-guaien-3-one |